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We aim to investigate whether reinstatement of cortical representations are necessary for successful memory retrieval.
The objective of the present trial is to investigate the safety of an allogenic tumor cell lysate loaded onto autologuous dendritic cells (AlloDen) in patients with malignant mesothelioma (MM). Heretoo we will perform a phase I study with a…
To study whether either early 18F-FDG or 18F-FLT PET is superior in detecting response to treatment with the combination of vemurafenib plus cobimetinib (GDC-0973) compared to standard response assessment with CT and to evaluate whether, and which,…
The primary objective is to study attachment in young children through skin-warming.
The primary aim of this project is to examine the impact of heart failure on functional sympatholysis.
In this study the test characteristics of the early structural ultrasound examination (SUE) (at 13-14 weeks) will be evaluated and compared the those of the standard SUE/AUE at 20 weeks. Also, the amount of (in-)conclusive examinations and the…
This research proposal aims to examine three broad research questions.The first research question concerns the longitudinal development of attachment of Chinese adoptees. This study provides the opportunity to shed light on the development of…
Primary objectiveTo detect the difference in mean arterial blood pressure between conventional APRV settings and APRV settings based on EIT measurements, in patients with ARDS.Secondary objectivesImproved dorsal ventilation distribution on EIT…
The aim of this prospective cohort study is threefold: (1) for a better understanding of MTSS' underlying pathophysiology, (2) to assess the QU's reliability in healthy subjects and subjects with MTSS and (3) to assess the validity of QU…
In breast-conserving surgery, there is evidence that approximately 30% of women receive a suboptimal or poor aesthetic outcome; however there is currently no standardised method of identifying these women.The PICTURE project aims to address these…
Changes in the Fibtem measurements during the first 24 hours after the start of the operation.
1. To assess the effects of 3 months neoadjuvant androgen ablation with enzalutamide on the surgicial margin status of men with non-metastasized prostate cancer.2. To properly evaluate the effects of androgen ablation on gene expression, analyses of…
The purpose of this study is to develop a sleep self-report instrument for people with a mild intellectual disability (SSR-ID) and to assess construct validity of the SSR-ID by showing its association with sleep parameters measured by actigraphy.
The objective of ths study is to investigate whether use of Tranylcypromine, a monoamine oxidase inhibitor, results in increased expression of HbF in adults. If this is the case, we will use the results of this study to design follow-up research…
Primary Objective:• Intracardiac blood total flow and maximum flow velocity measured by 4D MR, and compared with 2D MR.Secondary Objective(s):• Intracardiac pressures as assessed by 4D MR , compared with 2D MR, invasive catheterization and…
The primary objective of this study is to evaluate the ability of PET-MRI ( PET, DWI and DCE-MRI) to detect and locally stage breast cancer in patients.
The purpose of this study is to evaluate the effect of PRRT with 177Lu-octreotate on circulating NET transcriptomes. In particular, the variation of circulating NEN transcripts will be correlated to the response to PRRT to test whether this analysis…
The primary objective of the study is to evaluate the effects of orally administered metformin on the immune and metabolic responses of stimulated peripheral blood mononuclear cells (PBMC*s) and macrophages from healthy individuals.
Evaluation of the accuracy of the sentinel node procedure in bladder cancer patients.
The PICTURE project aims to address these issues by providing objective tools, tailored to the individual patient, to predict the aesthetic outcome of local treatment. Using a combination of 3D photography and routinely acquired radiological images…