18 results
Primary Objectives:- Determine the effect of pulmonary vasodilatation on indexed cardiac output during simulated exercise.- Characterization of structural properties of small pulmonary arteries.Secondary Objectives: - Investigate the effect of…
Primary obejective is the evaluation a ventral patch is associtaed with less complications than a conventional mesh for epigastric and umbilical hernias. Complications are defined as unexpected events necessitating a treatment within the period of…
To determine if orteronel plus prednisone improves radiographic progression-freesurvival (rPFS)To determine if orteronel plus prednisone improves overall survival (OS)
The study objective is to evaluate the clinical outcome of percutaneous aortic valve implantation in consecutive *real world* patients with severe aortic valve stenosis intended to be treated with the Medtronic CoreValve System.
The primary objective of this clinical investigation is to assess the safety and effectiveness of the Perceval S-valve at 12 months after implantation when used to replace a diseased or dysfunctional aortic valve or aortic valve prosthesis. The…
A new surgical device for the creation of compression anastomoses, the ColonRing*, which is nickel- titanium based, has been introduced. Safety and efficacy of the device have been established in previous clinical studies and the device has been…
The aim of the present study is a performance evaluation of INNOVANCE® PFA P2Y. The first objective is the determination of a reference interval for the Intended Use Population (patients eligible for Clopidogrel therapy). This will be done by…
does the use of fluticasone as an inhaled corticosteroid influence the determination of saliva cortisol?
The possibility to identify the risk of rupture of a carotid plaque will have tremendous impact in clinical decision making. Selection of candidates from surgery is based mainly on duplex ultrasonography, where now only the size of the stenosis is…
- Examine the reproducibility of the non-volitional endurance test in healthy subjects. The hypothesis is that the non-volitional endurance test is reproducible.- Comparing arm and leg muscle endurance in healthy subjects. It is expected that arm…
In this study, we want to find the anesthetic technique with the highest patient satisfaction, best surgical and anesthesiological conditions and the technique with the highest time efficiency. We compare three anesthetic techniques.
1. to compare the extent of reversal of left ventricular remodelling at 3 months and 1 year after a TAVI procedure between patients with a TAVI-induced LBBB and patients without a LBBB; 2. comparison of strain patterns in TAVI-induced LBBB (as being…
Primary objectiveTo compare the wear rate 60 months after THA of HXLPE stabilized with vitamin E versus conventional UHMWPE for total joint arthroplasty. Secondary objectives- To compare the wear rate at 3,12, 24 and 60 months after THA between…
To evaluate the accuracy of trained hypo-alert dogs and to evaluate the quality of life of patients with such a dog.
The development and optimization of new and existing MRI protocols and processing techniques required for advanced anatomical and functional imaging in the research and clinical setting.
To study activity in the reward-circuitry of the brain in patients suffering from cachexia induced by cancer.
We aim to develop three cognitive profiles to assess FTDr in HD patients; 1) Fit to drive, 2) No longer fit to drive, and 3) Dubious fit to drive and no longer fit to drive. The profiles will be determined with classic neuropsychological tests,…
To evaluate safety and clinical performance of the investigation product (drug-eluting absorbable metal stent system)