25 results
The main purpose of this study is to determine if KW-0761, an investigational drug will work against cutaneous T-cell lymphoma (CTCL) that has failed to respond to other treatments, and to evaluate its side effects. An investigational drug is one…
The aim of this study is to examine the daily level of activities and participation after LTH in children and adolescents (6-18 years) and to identify possible predictors. In addition, experimental research is done in a subgroup to measure the…
To examine the 1- and 3-year prognostic value of the CAR-test in patients with peripheral artery disease regarding the occurrence of vascular complications and the progression of PAD
To study prevalence and consequences of cognitive, psychological, social and functional decline in elderly breast cancer patients, in comparison to a population elderly without breast cancer.
Determine wether or not a strategy based on molecular analysis is effective in improving the PFS
Primary Objective: The main objective is to gain insight into the functional and structural neural correlates of success in foreign language learning. To this end, fMRI and DTI data will be acquired together with behavioral responses from healthy…
To investigate whether a short CBT intervention for sexual rehabilitation is feasible for patients (and their partners) and professionals. The available literature underscores the importance of sexual problems after pelvic RT and the need to develop…
To investigate the effectiveness of Mindfulness Based Compassionate Living (MBCL) in recurrent depressive patients.
Investigate whether switch from a non-nucleoside reverse transcriptase inhibitor (NNRTI)- or protease inhibitor (PI)-based regimen to a raltegravir-based regimen results in reduced platelet reactivity, reduced platelet-leukocyte aggregate formation…
Identification of the molecular and cellular muscular mechanisms associated with aging in rotator cuff muscles with radiological quantification and clinical data.
In the current study we will apply the Elfitor and collect its derived parameters during nociceptive stimulation in healthy volunteers without and with the administration of a low-dose opioid analgesic. Our study aim is to assess whether the various…
To gain insight into the measurement properties of three questionnaires (part I) and the measurement properties of the upper limb functional capacity evaluation (part II). To gain insight in the effects of disorders of hand or wrist on health-…
Determine the effect of rectus femoris transfer on stroke survivors walking with a stiff knee gait on functional-, activity- and participation level.
To evaluate the effect of OPEP use on respiratory symptoms in patients with COPD or chronic bronchitis with excess mucus in daily clinical practice.
Primary Objective: Test the capacity of drug candidates to specifically inhibit the signalling pathways they target in human blood cells in vitro in the setting of human whole blood.Secondary Objective(s): Test whether drug candidates exert…
The objective of the study is to assess the performance of topical negative pressure therapy application with Prevena* Incision Management System (IMS) versus standard conventional wound therapy (SCWT) on closed median sternal incisions in patients…
The aim of this study is to evaluate the changing over time of AA levels in plasma and in leukocytes before and during chemotherapy treatment for several different groups of patients and compare that to healthy controls.
Assessment of safety and clinical performance of the DREAMS 2nd Generation in de novo coronary artery lesions.
To document the initial stabilty of the Optimys stem with radiostereometric analysis in the first 30 patients, and to perform a clinical follow up of at least 150 patient treated with this implant to document the outcome.
Main objective: To study the level of (proneness to) shame among patients with a borderline personality disorder following MBT at a general mental health institution in the south of the Netherlands (GGz Breburg) at the start of treatment as well as…