46 results
The main purpose of this study is to determine if KW-0761, an investigational drug will work against cutaneous T-cell lymphoma (CTCL) that has failed to respond to other treatments, and to evaluate its side effects. An investigational drug is one…
To examine the 1- and 3-year prognostic value of the CAR-test in patients with peripheral artery disease regarding the occurrence of vascular complications and the progression of PAD
To study prevalence and consequences of cognitive, psychological, social and functional decline in elderly breast cancer patients, in comparison to a population elderly without breast cancer.
Determine wether or not a strategy based on molecular analysis is effective in improving the PFS
Primary Objective: The main objective is to gain insight into the functional and structural neural correlates of success in foreign language learning. To this end, fMRI and DTI data will be acquired together with behavioral responses from healthy…
To investigate whether a short CBT intervention for sexual rehabilitation is feasible for patients (and their partners) and professionals. The available literature underscores the importance of sexual problems after pelvic RT and the need to develop…
To investigate the effectiveness of Mindfulness Based Compassionate Living (MBCL) in recurrent depressive patients.
Identification of the molecular and cellular muscular mechanisms associated with aging in rotator cuff muscles with radiological quantification and clinical data.
This study will be a prospective, placebo controlled, randomised phase 2 single centre study with the primary objective to evaluate the safety and tolerability of 2-IB when administered to patients with AIS due to LVO, treated with IVT and/or EVT.…
Primary objectiveThe primary objective is to evaluate whether a standard pre- and postdilatation of the modern DES results in a more optimal stent implantation compared to DS as evaluated by OCT in patients with stable coronary artery disease.…
In this trial we will study the utility of PerfusiX-Imaging for perfusion assessment of the gastric conduit in comparison with the standard of care.
To confirm our STARNL-1 pilot efficacy and safety data in a larger cohort and obtain insights in the mechanism of action by evaluating electro-anatomical alterations of stereotactic arrhythmia radiotherapy in patients with therapy refractory…
In the present study, we propose to investigate the efficacy of pharmacological treatment of GDM (using metformin) by the pathophysiological cause of hyperglycemia, namely reduced insulin sensitivity or reduced insulin secretion. Primary Objective:…
To document the initial stabilty of the Optimys stem with radiostereometric analysis in the first 30 patients, and to perform a clinical follow up of at least 150 patient treated with this implant to document the outcome.
To establish the safety and effectiveness of the Edwards SAPIEN 3/ SAPIEN 3 Ultra Transcatheter Heart Valve (THV) in subjects with moderate, calcific aortic stenosis (AS)
The primary objective of the study is to determine feasibility of CEA assessments at home using (automated) capillary sampling. Home based (automated) capillary sampling will be considered feasible if a success rate of 85% or greater has been…
The primary aim of this RCT is to evaluate whether the use of oral supplementation of hydrolysed collagen/vitamin C in addition to usual care (education, load management and PTLE) is superior to usual care and placebo on VISA-P score after 24 weeks…
Primary Objective: The main goal of this study is to provide evidence that steering saccharolytic/proteolytic fermentation by a specific indigestible fibre mixture supplemented against the background of a high-protein diet optimizes beneficial and…
Primary Objective:• To evaluate the effect of an online 12 week plant-based dietary program compared to usual diet on change in glycated hemoglobin and estimated relative CVD risk in persons with type 2 diabetes. Secondary Objective(s): • To…
Primary Objective: Assess the ability of MRCP+ and LMS to detect change in total biliary volume and cT1 value, 8 weeks after endoscopic treatment of dominant strictures, by a clinical decision rule.Secondary Objective(s): Assess natural course of…