65 results
The main hypothesis is that circulating inflammatory mediators are the main causative factor for the emergence of generalized osteoporosis in patients with Rheumatoid Arthritis (RA). 1.Does the serum of patients with active RA, containing…
To compare sex differences in brain functioning using functional magnetic resonance imaging (fMRI) in healthy pre-pubertal boys and girls with a group of children diagnosed with GID. Subjects will have a second fMRI scan, as soon as they enter…
In this study, we want to investigate whether obese children perform differently than normal weight children (data already generated) on tasks of sensitivity to reward and executive functioning.
This project aims to understand the symptomatology PD in the light of functional brain interactions, in the hope of elucidating the role of the frontal striatal system to behaviour.
Aims:a) Understand persistence and/or plasticity of the brain correlatesb) Understand specificity of the brain correlatesQuestions:a) Which neural correlates of OCD are state dependent and thus normalized after successful treatment?b) Which neural…
1. Immunology and Pathology:To determine the immune response of patients with simple and complex appendicitis in order to identify markers which distinguish between simple and complex appendicitis.2.Clinical and Imaging:To analyze the differences in…
Determining the role and influence of genetics, their polymorphisms and immunologic phenotype in arteriogenesis in patients with obstructive coronary artery disease (CAD).
Within this project we aim to determine the energetic conditions that underlie the transition to hypertrophy of the HOCM heart. A prospective comparison will be made between results of PET, MRI and function of cardiac myofilaments (in vitro). Also,…
Primary Objective: To gain more insight in the genetic susceptibility for AIH. For this we will study the presence of candidate genes in AIH patients, study genetic similarities with other auto-immune diseases and perform a whole genome association…
The primary aim of this study is to prospectively assess the incidence of pulmonary embolism in patients undergoing abdominal flap breast reconstruction.
The present study aims to investigate several cognitive and emotional factors associated with chronicity of alcohol dependence.
To investigate whether propriocepsis or reflexes are present after nerve reconstruction
1. Does mPAT directly impair vasoreactivity to insulin and acetylcholine ex vivo in arterioles obtained from muscle biopsy in lean and obese individuals?2. Is obesity in humans associated with the accumulation of mPAT and an inflammatory mPAT…
The primary objectives are:- to identify predictive factors for fatigue in cancer survivors on long-term sick leave. - to develop a prognostic instrument by which insurance physicians can assess future functional abilities, related to the work…
We will investigate endothelial function before and after bariatric surgery.
The main aim of this project is to identify genetic and metabolic risk factors for mild MR and borderline intelligence.
In this trial we will investigate the following hypothesis:- Uremic vasculopathy develops, not only in large and medium sized conduit vessels, but also in the microcirculation.- There is a relationship between the rate of microcirculatory…
This study evaluates glomerular function in children with a solitary functioning kidney. Furthermore anthropometric data is gathered about waist-hip ratio and subscapular skinfold thickness. Anthropometric characteristics can be both a cause as an…
The purpose of this study is to investigate the association between T cell compartment composition and vitamin D status in MS patients, with particular interest for regulatory T cell functionality.