97 results
The primary objectives are:- to identify predictive factors for fatigue in cancer survivors on long-term sick leave. - to develop a prognostic instrument by which insurance physicians can assess future functional abilities, related to the work…
The aim of this MRI study is to understand how neurodegeneration in MS (in vivo) is related to other facets of MS pathology, i.e. inflammatory (T2) lesions, black hole (T1) lesions, cortical lesions and damage of the normal appearing brain tissue.…
To assess the prevalence of BHD among patients with spontaneous sporadic and familial pneumothorax.
The primary objective of this study is to determine the response rate of electrochemotherapy in head and neck cancer. Secondary objectives are to monitor local and systemic side effects and adverse events and to determine quality of life before and…
We will investigate endothelial function before and after bariatric surgery.
We aim to observe in whole blood at patients core temperature and normotemperature how mild therapeutic hypothermia affects coagulation and in particular fibrinogen, in post cardiac arrest patients.
To evaluate the feasibility and (cost) effectiveness of an intervention to improve the quality of dementia care and the wellbeing of home dwelling persons with dementia and their main informal caregiver.
Compare usual care in patients with treatment resistant heart failure with additional ultrafiltration by peritoneal dialysis.
- Primary objective:To evaluate the flow cytometric characteristics of the bone marrow compartment before and during treatment with Exjade® in low and intermediate-I risk myelodysplastic syndromes.- Secondary objectives:To correlate the flow…
The primary study objectives are: (1) to determine whether an internet-based guided self-help intervention is effective in reducing symptoms of depression in glioma patients; (2) to determine the impact of the intervention on the HRQOL of both…
The main hypothesis is that circulating inflammatory mediators are the main causative factor for the emergence of generalized osteoporosis in patients with Rheumatoid Arthritis (RA). 1.Does the serum of patients with active RA, containing…
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This will be a pilot study that aims to gain insight into the effect of Gaucher disease on bone metabolism. For this purpose we formulated the following research questions:What is the effect of inflammatory factors in the serum of patients with…
The main goal of the trial is to establish whether laparoscopic incisional hernia repair is superior to conventional open incisional hernia repair in terms of cost-effectiveness. This is measured through length of hospital stay and quality of life.…
Primary Objective: We want to estimate cut off values for clinically appropriate hypoperfusion of the pharyngeal mucosa and the skin in the neck. Secondary Objective: We want to compare perfusion rate of PTL to perfusion rate in STL in order to…
This study has been transitioned to CTIS with ID 2024-513843-10-00 check the CTIS register for the current data. Primary objective: Assess the short term safety and tolerability of 68Ga-SATO in pediatric patients with NBLSecondary objectives: -…
To understand the mechanism of action of OA for the treatment of de novo, severely calcified coronary lesions prior to stent placement using optical coherence tomography (OCT) and to assess stent expansion, based on OCT derived minimal stent area (…
Primary Objective: To assess the safety profile (AEs, SAEs) on combined treatment with tamoxifen and testosterone.Secondary Objectives:• AR to ER ratio on baseline FES- and FDHT-PET imaging (assessed per lesion and per patient by quantitative…
The overall objective of this study is to investigate the potential immunomodulatory effect of sugammadex as seen in previous ex vivo experiments. Specified, the main objective is to investigate the effect of administration of sugammadex without…
The primary objective of this research is to determine the prevalence and magnitude of loss of benefit from DBS stimulation in patients who underwent DBS surgery for upper extremity tremor that was refractory to medical management. The secondary…