84 results
Primary Objective: comparing hemodynamic stability provided by titration of esmolol in addition to standard perioperative care including low-dose metoprolol to placebo and standard care.Secondary Objective(s): -comparing the incidence of…
The primary objective of the present trial is to evaluate, during a 4-week period, the efficacy of a Zendium dentifrice containing enzymes, colostrum, lysozyme & zinc, in combination with the use of a manual toothbrush with respect to plaque…
The main objective is to translate and adapt the Adolescent Cannabis Check-Up (ACCU) to the Dutch context and setting, and to evaluate its effects on the cannabis use of adolescents in the Netherlands. The Dutch version of the ACCU is called Wiet-…
The present study aims at comparing the post-operative lung injury of a lung*protective mechanical ventilation strategy (with the use of higher levels of PEEP and intra*operative recruitment maneuvers) with conventional mechanical ventilation (lower…
1) To evaluate the efficacy of knee-ankle-foot orthoses (worn by night) in preventing a decrease of range of motion to ankle dorsiflexion in children with cerebral palsy (Clinical part). 2) To evaluate the effect of night-worn knee-ankle-foot…
Patients in whom a permanent (end) colostomy is created in (semi) elective setting are randomised between the placement of a polypropylene mesh during stoma creation and the classic method without a mesh. Primary aim: Does the use of a lightweight…
The primary objective of this study is to determine whether clopidogrel + best medical treatment is superior to best medical treatment only in preventing:A) cardiovascular death, MI, stroke, or severe ischemia of the coronary or peripheral arterial…
Main object Is there a reduction of the acute peripheral neuropathy complaints of patients with advanced or metastatic colorectal cancer due to the infusion of heated oxaliplatin?Does the quality of life of these patients improve?Secondary objectThe…
The aim of this study is to evaluate whether a 30-minute episode of helium breathing in humans affects the ability of the immune system to respond to ex vivo stimulation in whole blood taken from healthy volunteers.
The current proposal aims at testing an innovative, implementable, effective intervention strategy towards stopping of passive smoke exposure in children at risk for asthma.
The primary goal of this trial is to demonstrate that a physical activity program, which consists of an exercise program and follow-up care, under supervision of a specialized physiotherapist can prevent the frequently observed decline in global…
The Claret device (Claret Inc.) is an Embolic Protection Device (EPD) consisting of two nitinol baskets to be introduced through the right radial artery. One basket is positioned in the brachiocephalic trunk, the other in the left common carotid…
Measurement of the pain index, NoL, during laryngoscopy, intubation and skin incission during variations in de level of propofol and remifentanil.
To determine the efficacy of antibiotic prophylaxis after a tick bite in the Dutch setting, in relation to tick infection, tick engorgement and attachment time.
To determine if adjusting endotracheal tube cuff pressure after placement of a retractor during anterior cervical spine surgery prevents postoperative dysphagia. Furthermore laryngo-tracheal complaints (hoarseness and sore throat) will be scored.
The primary objective of this study is to investigate the effect of a meal-like amount of dietary protein prior to sleep on postprandial muscle protein synthesis in healthy young and elderly men, following exercise, during the night. Furthermore, as…
The aim of the study is to evaluate the effectiveness of FRIENDS for Life as an indicated school-based prevention programme for children with early or mild signs of anxiety or depression.
the purpose of this study is to investigate the efficacy of liraglutide to lower glucose and to influence coagulation activation during and after hip surgery
To study if there is a role for prophylactic VZV vaccination prior to transplantation to boost the patients B- and T-cell repertoire and thereby reducing the incidence and morbidity associated with herpes zoster.
The primary objective is to study the effects of 12 weeks of treadmill training with virtual reality on neural plasticity in comparison to the effects of treadmill training without virtual reality.Secondary objectives are to investigate the role of…