167 results
Is, when EE is kept constant, replacing sitting time by NEA more effective than exercise in improving glucose control in people with DM2?
1 Assessment whether using a nerve-sparing exposure of the aortoiliac tract during vascular reconstruction will lead to a neurophysiologically intact sympathetic pathway to the intra-pelvic organs and thus to an intact postoperative function.2…
To compare ticagrelor with clopidogrel treatment on the risk of cardiovascular death, myocardial infarction and ischaemic stroke in patients with established peripheral artery disease.
Examine the impact of 7-day daily ischemic preconditioning on brachial artery endothelial function (measured as FMD%) in the dominant arm (i.e. local effect: primary objective) and contra-lateral arm (i.e. remote effect: secondary objective) in…
To compare the blood pressure lowering effect of thiazides against calcium channel blockers in CNI-induced hypertension.
To examine the impact of age and physical fitness on the ability of ischaemic preconditioning to protect endothelial damage in response to ischaemia reperfusion injury in healthy humans. A secondary objective is to explore the role of Toll-like…
We will identify factors that interfere with the beneficial effects of exercise on the vasculature in T2DM.
The objective of the study is to compare the effects of homogenized, unhomogenized and skimmed milk with butter on postprandial metabolism in healthy overweight men.
1. To investigate the presence of risk factors for CVD (i.e. overweight/ obesity, hypertension, diabetes and dyslipidemia,) among the Ghanaian population in Amsterdam.a) To investigate levels of detection, treatment and control of hypertension among…
Primary objective: The primary objective of the study is to determine the effect of oral dipyridamole treatment on the innate immune response induced by a lipopolysaccharide (LPS) challenge. Various pro- and anti-inflammatory cytokines will be…
To prove that lymph vessels in the legs can be visualized with methylene blue, so they can be spared during surgery, what possibly may lead to decreased postoperative lymph edema.Hypothesis: Methylene blue visualizes lymph vessels in the legs, so…
The primary objective is to determine the effect of (1) increased sodium intake and (2) increased potassium intake on flow-mediated dilation (FMD) and systolic blood pressure (SBP) in untreated (pre)hypertensive subjects
For pregnant women with non-severe non-proteinuric maternal hypertension at 14-33 weeks, will *less tight* control (target dBP of 100mmHg) vs. *tight* control (target dBP of 85mmHg) increase or decrease the likelihood of pregnancy loss or neonatal…
a. To study whether a specific set of biomarkers is associated with PE with DVb. To study whether a specific set of biomarkers is predictive of PE with DV.
The primary purpose of this study is to determine the relation between a physically active lifestyle and the primary and secondary prevention of diseases and death.Using an online questionnaire, we will approach all civilian participants of the…
The possibility to identify the risk of rupture of a carotid plaque will have tremendous impact in clinical decision making. Selection of candidates from surgery is based mainly on duplex ultrasonography, where now only the size of the stenosis is…
The primary goal of this trial is to demonstrate that a physical activity program, which consists of an exercise program and follow-up care, under supervision of a specialized physiotherapist can prevent the frequently observed decline in global…
Primary aim of the study is to investigate if motivational interviewing can be an effective way to motivate en stimulate patients with recent TIA or ischemic stroke to change their lifestyle and maintain this healthy lifestyle. Moreover we will…
The general aim of this project is to evaluate the effectiveness, safety and costs of a medication withdrawal policy compared to usual care in general practice in patients who are currently treated for hypertension and/or hypercholesterolemia, but…
To study the protective effect of pre-treatment with metformin on flow mediated dilation after 20 minutes ischemia and 20 minutes reperfusion. If metformin treatment indeed limits endothelial IR-injury, a second study will be performed in the same…