Search for a trial

Arterial stiffness, Blood Pressure and Cardiac output study; ABC-study;A Prospective, Multidisciplinary study of arterial stiffness measures in patients treated for aortic aneurysms in relation to blood pressure and cardiac output

Zie document PROTOCOL SYNOPSIS ABC study

Characterization of ascending aortic flow patterns and vessel wall in patients with aortic valve stenosis before and after surgical valve replacement: a 4D Flow Magnetic Resonance Imaging study.

We aim to i) describe flow patterns and flow-related dynamics in the ascending aorta of patients with aortic valve stenosis, ii) compare these flow parameters before and after surgical aortic valve replacement and iii) compare flow parameters with…

Clinical relevance of Positron Emission Tomography (PET) imaging following endovascular aneurysm repair using the Nellix endoprosthesis.

To determine FDG uptake following uncomplicated EVAR using the Nellix endoprosthesis. Does uncomplicated EVAR using the Nellix endoprosthesis result in increased FDG uptake and false positive PET imaging? .

Silent MRA of intracranial arteries: follow-up of aneurysms treated with coils

Test the optimized MRI sequences/technology against commercially-available, clinical MRIsequences in terms of image quality, signal-to-noise ratio (SNR), contrast-to-noise ratio(CNR), speed, and accuracy/reproducibility of extracted quantitative…

An exploratory open-label PET-observer-blinded pilot study to evaluate the effect of 3 and 12 months treatment with Aliskeren-based versus amlodipin-based antihypertensive treatment in patients with a small abdominal aortic aneurysm and mild to moderate hypertension on aneurysmal FDG-uptake as measured with FDG PET

Main objective: * To evaluate the effect and variation of 3 and 12 months treatment with Aliskeren-based versus amlodipine-based antihypertensive treatment on aneurismal FDG- uptakeExploratory objectives: * To explore the effect of 3 and 12 months…

Prevalence of vascular pathology associated with self-reported symptoms of digital ischemia in (a)symptomatic elite male volleyball players in the Netherlands

1a) To determine the prevalence of digital pathology, possibly as a result of digital emboli, in the dominant hand in symptomatic and asymptomatic elite Dutch male volleyball players. 1b) To determine the association between the presence of digital…

APC-trial: Accuracy, Precison and Concordance of Ventricular Field Recognition in patients after open Abdominal Aortic Aneurysm Repair.

Aim of the studyIn this prospective, observational trial, we aim to investigate the accuracy, precision and concordance of VFR in patients after open abdominal aortic aneurysm (AAA) repair during their stay in the ICU. CO measurements obtained with…

Prevalence of vascular pathology associated with self-reported symptoms of digital ischemia in (a)symptomatic elite male volleyball players in the Netherlands

1a) To determine the prevalence of anomalies of the PCHA in the dominant shoulder in symptomatic and asymptomatic elite male volleyball players. 1b) To determine the association between anomalies of the PCHA in the dominant shoulder with the…

Prevalence of vascular pathology associated with self-reported symptoms of digital ischemia in symptomatic and asymptomatic elite male and female beach volleyball players during the Grand Slam Beach Volleyball 2013 the Hague, the Netherlands

1a) To determine the prevalence of anomalies of the PCHA in the dominant shoulder in symptomatic and asymptomatic elite male and female beach volleyball players. 1b) To determine the association between anomalies of the PCHA in the dominant shoulder…

Screening Cardiovascular patients for Aortic aNeurysms

The research focuses on the active screening of high prevalence patients and the diagnosis of AAA. This study aims to establish an effective screening protocol and determining a higher prevalence in patients with PAD and patients with carotid…

Hemodynamic consequences of intra arterial treatment of intracranial aneurysms using non-invasive quantitative flow measurements from arterial spin labeling techniques in high field strength MRI.

Primary objective:- Determining the extent to which perfusion territories of the larger intracranial arteries are affected by endovascular treatment of intracranial aneurysmsSecondary objectives:- Defining the relationship between collateral…

Fattening of the Adventitia as MR Imaging basEd biomarker in AAA patients (FAME)

To determine whether it is possible to identify adventitial fattening of the aortic wall in patients with an abdominal aortic aneurysm using MRI techniques and use this adventitial fattening as a new biomarker for AAA patients.

Biological and biochemical markers of aneurysm wall degradation; towards non-invasive wall strength analysis.

To identify possible in vivo biochemical and biological markers related to aneurysm wall strength.

Arterial spin labeling MRI in the follow-up of therapeutic internal carotid artery occlusion

- To assess the number of de novo aneurysms in patients who underwent therapeutic ICA occlusion more than 5years ago.- To assess infarct load in patients who underwent therapeutic ICA occlusion more than 5 years ago.- To evaluate the distribution of…

Hemodynamic measurements and vessel wall property assessment in patients with abdominal aortic aneurysm during pre-operative dynamic MRI examinination.

To assess the influence of bloodpressure, wall thickness, wall properties, and geometry changes throughout the cardiac cycle on the wall stress calculations. Previous analysis were performed with an assumed bloodpressure value, an uniform wall…

Additional value of 3D rotational angiography in the detection of intracranial aneurysms.

Prospectively compare the sensitivity of 2D DSA and 3D rotational angiography in the detection of intracranial aneurysms.

MRI molecular imaging of (inflammatory) macrophages as a predictor of abdominal aortic aneurysm progression

I. The main objective of our study is to differentiate between patients with stable or slowly growing AAA from patients with rapidly growing AAA. We believe that inflammation is a major player in the process of growth. In order to achieve our main…

Gadolinium-enhanced aneurysm wall imaging of unruptured intracranial aneurysms

1. To assess the prevalence of gadolinium-enhancement of the aneurysm wall in patients with unruptured aneurysms2. To assess the relation between gadolinium-enhancement of the aneurysm wall and a. The use of anti-inflammatory drugs (including…

Follow-up of intracranial aneurysms treated with the Surpass flow diverter: comparison of subtraction CTA and DSA. Part II: a retrospective selected case series.

Primary objective: -To determine the accuracy of sCTA compared to DSA in the visualisation of the degree of occlusion in the FU of intracranial aneurysms treated with Surpass. Secondary objectives:-To determine the accuracy of sCTA compared to DSA…

Follow-up of intracranial aneurysms treated with the Surpass flow diverter: comparison of subtraction CTA and DSA. Part I: a prospective case cohort study

Primary objective: - To determine the accuracy of sCTA compared to DSA in the visualisation of the degree of occlusion in the FU of intracranial aneurysms treated with Surpass. Secondary objectives:-To determine the accuracy of sCTA compared to DSA…