135 results
The primary objective of this study is to investigate if the use of Heli-FX EndoAnchors in conjunction with placement of aortic stent grafts under instructions for use (IFU) conditions in aneurysms with a wide neck is superior to treatment with…
Abdominal Aortic Aneurysm Sac Healing and Prevention of Endoleaks - A Prospective Multicenter Study.
To evaluate the safety of IMPEDE-FX Embolization Plug and/or IMPEDE-FX RapidFill to fill a AAA sac outside of an EVAR stent graft, and the efficacy of the IMPEDE-FX Embolization Plugs to reduce the volume and/or diameter of the AAA sac and/or the…
The leading hypothesis is: Endoleaks type II are prevented when AneuFix is prophylactically used during EVAR procedures. The primary (performance) objective is to assess the feasibility to fill the AAA sac after EVAR during the same procedure, and…
Primary objective: To investigate if the presence of aneurysm wall enhancement predicts aneurysm instability in the long-term. Secondary objective: To investigate if the absence of aneurysm wall enhancement predicts aneurysm stability in the long…
The aim of this prospective one-year follow-up study is to investigate whether preoperative 3D US measurements of AAA characteristics with and without the use of a US contrast agent are comparable to CTA. The secondary objective is to identify…
The primary objective of the study is to assess the feasibility to treat type II endoleaks with Aneufix ACP-T5 successfully.The secondary objectives of the study are to assess the:- Clinical success rate defined asOccurrence of adverse events and…
Primary Objectives: •To determine the correlation between AAA growth and the evolution of serum levels of proteases and cytokines.•To determine the correlation between AAA rupture and the evolution of serum levels of proteases and cytokines.•To…
Relate aneurysm hemodynamics to aneurysm configuration and growth to obtain insight in the hemodynamic pathophysiology of aneurysm growth in order to improve prediction of aneurysm rupture.
In a phase II study we will evaluate safety and proof-of-concept of acetazolamide in patients with aneurysmal SAH. The primary aim of this study is to evaluate whether acetazolamide improves cerebral perfusion as measured with magnetic resonance…
The purpose of the Endurant Evo International Clinical Trial is to evaluate the safety and effectiveness of the Endurant Evo AAA Stent graft system for endovascular treatment of subjects with infrarenal abdominal aortic or aortoiliac aneurysms.
The current study aims to establish age-dependent and sex-specific normal values for novel imaging biomarkers using 4D flow MRI and CFD.
The objective of this study is to see if the apposition and position of the endograft in the aorta changes between an upright and laying down position of the patient. An upright position with other geometrical parameters than in supine position…
1: Feasibility: to assess whether 4D flow MRI, DCE-MRI and T1/T2 mapping sequences can produce high-quality images that enable the calculation of the primary parameters wall shear stress (WSS), kinetic transport constant (Ktrans) and T1/T2…
The aim of the current study is to determine whether a *liberal* strategy of maintaining Hb concentrations above 9 g/dL would result in a different neurological outcome when compared to a *restrictive* approach to red-cell transfusion to avoid…
Our main objective is to improve the level of SDM during vascular surgical consultations in which a treatment decision is to be made, with the use of DSTs. Our secondary objectives are to improve SDM as experienced by both patients and physicians,…
The goal of this study is to investigate whether BOLD MRI can predict the occurrence of buttock claudication after coiling of the internal iliac arty. The BOLD technique will be used to measure blood supply parameters of the gluteal muscle during…
The current project aims to implement male-female specific insights into aortic root and ascending aorta characteristics into clinical practice, allowing better identification of high risk Thoracic Aortic Aneurysm (TAA) patients and better timing of…
Information on the dynamics and shape of the stent graft and stented target vessels and how these change over time will improve our understanding about the fixation and/or sealing of the device, which may help in stent graft selection and in…
The aim of this prospective 2-year follow-up study is to investigate the predictive capacity of the CAR-test in comparison to the SMART risk score for progression of the abdominal aorta aneurysm and development of cardiovascular events in patients…
The aim of this explorative study is to investigate the correlation between the magnitude of the abdominal aorta and the carotid artery diameter and blood flow responses during the sympathetic stimulation (using the cold pressor test) between…