47 results
- To elucidate whether simultaneous measurement of brachial BP may improve the accuracy of assessment of interarm BP differences compared with sequential interarm BP assessment
The prime objective of the IMPROvED project is to develop a clinically robust predictive blood test for pre-eclampsia, using innovative technologies and utilising novel metabolite and protein biomarkers. This blood test is targeted to all first time…
Answering the question about the influence of ageing on the relationship between systemic flow and pressure on the one hand and cerebral perfusion on the other hand.
We propose a 2-week randomized controlled, single-blinded pilot study to compare the health effects of a Paleolithic diet and an isocaloric reference diet (based on the *Guidelines for a healthy diet 2006*) on markers of the MetS which are risk…
The primary objective is to investigate if there are differences in the acute postprandial vasodilating effect between different protein sources and if these differences are associated with differences in the responses of vasodilating factors.…
Here we propose to perform a prospective, randomized, multicenter study that compares effectiveness of AVS with effectiveness of CT-scanning for the diagnosis of PA subtype. There is no criterion standard for accuracy of the diagnosis of PA-subtype…
The primary objective is to investigate if a salt-reduced diet leads to an increased reward response when exposed to lower salt concentrations in food.
This study has two principal aims. The first aim is to establish the relation between the auto-cuff response and target organ damage defined as difference in microalbumin/creatinin ratio. The second aim is to assess the difference in BP between…
In this study our overall aim is to more precisely determine which patients will benefit most from RSD by evaluating both outcome predictors and auxiliary effects (insulin sensitivity, central haemodynamics and inflammation) of this new intervention…
At the moment CA can only be assessed in laboratories that have been set-up to perform the specific measurements. This study tries to use a diversity of methods for measuring and analyzing CA and reach a method that is a simplified version of…
A study will be conducted to investigate whether screening for PE and growth restriction not associated with PE in the Dutch setting is feasible.
To evaluate whether cognitive function of formerly preeclamptics is diminished and correlated with dynamic cerebrovascular control properties using non-invasive measuring techniques (dynamic cerebral autoregulation, neurovascular coupling). Question…
To demonstrate that after a reduction in systolic blood pressure between 20 and 80mmHg within 3 months to reach a target of 140 mmHg, cerebral blood flow is not lower than prior to the start of treatment.
With a standardized approach in a population with difficult to treat hypertension we want to explore how frequenty PHA is a cause of hypertension and what the test characteristics of the aldosterone-renin ratio are. Additionally we want to…
Following the participants three more years will enable us to get a better overview of the consequences of the screening with regard to treatment, health, lifestyle modifications and illness perception with regard to obesity. Primary Objective: • To…
Main objective:Have formerly preeclamptic women, 5 to 10 years post-partum, a higher prevalence of a cardiovascular riskprofile compared to women with uncomplicated pregancies in history.
The objective of the study is to investigate whether the Out-Of-Office BPM device of Microlife, the WatchBP O3, is comparable to the Spacelabs 90217 device at 24h BP measurement. Secondary objectives: To investigate whether the implemented features…
1) To determine the prevalence of MetS in the patient population of the MMIJ in IJsselstein aged 20 to 70 years2) To assess the effectiveness of population screening for MetS by general practitioners in a medium-size city in the Netherlands
To assess if the studied TCD variables of cerebral autoregulation and hemodynamics are abnormal during preeclampsia. And if so, to determine if these changes are large enough to have potential value to determine a threatening cerebral dysfunction in…
Early Target Organ Damage in patients with Hypertension: a Magnetic Resonance Imaging (MRI) Approach
To assess early hypertensive induced target organ damage using Magnetic Resonance Imaging (MRI) technology. To relate microalbuminuria and low grade systemic inflammation to cardiac, cerebral and aortic target organ damage. Emphasis will be on young…