25 results
In view of this lack of evidence and strong practice variation we propose a randomized clinical trial in overweight and obese subfertile women, in which we compare the costs and effects of a six months structured lifestyle program, aimed at weight…
To design a multivariate prediction model of pregnancy outcome in women with PCOS with the intention to define intervention strategies for the future.
To investigate the effect of androgeninsufficiency on sexual function in women with POI. Also, to map the sexual dysfunction in different domains and compare this data to medically healthy women with sexal problems and medically healthy women…
Objectivesi)) To study whether reproductive hormones play a role in migraine susceptibility in malemigraine patients; ii) to study functionality of the trigeminal system prospectively duringinterictal and premonitory phases of the migraine attack (…
In this study the prevalence and kind of sexual and psychosexual problems will be assessed. Psychological well being is studied as well
To study how testosterone levels in muscle tissue compare to plasma levels in males.
This research proposal has multiple aims for research in women with WHO I, II or III status, including extended care and general health assessment, diagnosis/etiology, assessment of best approach/treatment, cardiovascular risk assessment, and…
To study whether there is an individual setpoint for the hypothalamus-pituitary-gonad axis in men
The objective of this observational study is the safe introduction of clinical applied IVM in The Netherlands. During this study, the number and quality of the oocytes and embryos will be studied as well as pregnancy development. Emphasis will be on…
1) To assess whether galactosemia women with ovarian failure are able to produce estradiol after exogenous (normally bioactive) FSH and LH gift 2) To characterize FSH glycan structures
The hypothesis is that women who have the Ser680Ser (SS) variant of the FSH receptor genotype, in comparison with women with the Ser680Asn (NS) or Asn680Asn (NN) variant, are less sensitive to FSH and because of that need higher dosages of FSH when…
The main objective of this prospective population based cohort study of patients with KD in the Netherlands and Flemish part of Belgium is to perform multiple tests (i.e. clinical and blood) and genomic profiling to discover possible biomarkers for…
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The overall aim of this study is to examine, in adult female CCS in the Netherlands, the effects of treatment in general, and the effects of different types of treatment, doses of drugs, radiation sites and doses, and age at time of treatment, on: 1…
More knowledge about the clinical aspects of the FMR2 gene mutation can complete the couseling. Carriers with the desire to start a family can take the chance on POF in consideration. The clinical symptoms of FXTAS can be differentiated from other…
Primary research questionDo obese PCOS women with reduced insulin sensitivity have HDL particles that have impaired anti-oxidative function in comparison with lean controls with normal insulin sensitivity?Secondary research questionDo obese PCOS…
To study whether higher estradiol levels in obese men are responisble for the lower testosterone levels also found in these men
to study the effect of estradiolapplication on gonadotropin relaese in young and older men in the abscense of circulating testosterone.
To explore the relationship between hormone levels and HRQoL in patients with TS and KS.
1. To assess the prevalence of severe male subfertility in adult male survivors of childhood cancer in relation to type and intensity of treatment and age at time of treatment. 2. To assess the diagnostic value of inhibin B and AMH for the…