412 results
The aim of the present study is to compare two methods for measuring continuous cardiac output (LiDCO and Physioflow) with the direct and continuous Fick method and continuous thermodilution during submaximal and maximal exercise in patients with…
Primary objectives are 1) pulmonary function in stable CHF, 2) COPD prevalence, under- and overdiagnosis in stable CHF patients, 3) systemic inflammation in stable CHF: is there a synergistic effect when COPD coexists? Secondary objectives are 1)…
Objective: -To investigate the effects of recombinant human erythropoietin (rHu-EPO) on myocardial perfusion and efficiency in patients with CHF using positron emission tomography (PET) and cardiac magnetic resonance (CMR).Secondary objectives: -To…
Determine the prolonged effect of a 12 week physical exercise program in congestive heart failure patients.
1.1 What are the self-perceived symptoms and care needs of patients with moderate to very severe COPD, CHF or CRF and to what extent do they differ from each other?1.2 Do these self-perceived symptoms and care needs relate to patients* daily…
We hypothesize that also in patients with diminished left ventricular ejection fraction or left ventricular hypertrophy, echocardiographic Doppler measurement of mitral inflow and venous pulmonary flow more reliably reflects actual left atrial…
The present study aims at comparing bedside JVP measurement using the so-called venous arch (veneuze boog) with modern echocardiography and NT-pro-BNP in patients referred for echocardiography with a suspicion of heart failure. The study also aims…
The aim of this study is examine the effect on clinical endpoints (death, readmission for heart failure and quality of life) by comparing two intervention groups (Disease Management with or without Telemedicine) with the control group (care as usual…
To investigate the genetic, genomic and proteomic basis of hypertension and susceptibility to hypertension-related target-organ damage (renal insufficiency and heart failure).
1. to compare the extent of reversal of left ventricular remodelling at 3 months and 1 year after a TAVI procedure between patients with a TAVI-induced LBBB and patients without a LBBB; 2. comparison of strain patterns in TAVI-induced LBBB (as being…
The primary objective of the study is to explore the efficacy of intensive bicycle exercise test to induce cardiac micro-injuries by measurement of serum concentrations of hs-troponin I in healthy volunteers. The secondary objectives of this study…
Main objective:Have formerly preeclamptic women, 5 to 10 years post-partum, a higher prevalence of a cardiovascular riskprofile compared to women with uncomplicated pregancies in history.
The objective of the current study is: - to enlarge the knowledge of the prevalence of heart failure and its management of nursing home residents with heart failure. - to get insight into the care dependency and quality of life of nursing home…
The primary objective of the study is to investigate the effect of sunitinib on ex-vivo atrial contractile force in absence and presence of ischemia-reperfusion. A secondary objective is to explore if atorvastatin or AICAR prevent sunitinib-induced…
To investigate whether the expression of renal water and sodium transporters in urinary exosomes is different in compensated versus decompensated liver and heart disease.
This study evaluates the difference in response to CRT between endocardial en epicardial left ventricular pacing. Secondly, we will evaluate the effect of simulated exercise by means of intravenous dobutamine on response to CRT and device…
The study is being conducted to evaluate whether continuous measurements of Heart Rate Turbulence (HRT), Deceleration Capacity (DC) and Acceleration Capacity (AC) can be used to predict decompensation in Heart Failure patients.Software algorithms…
The major research objective is:- to examine whether elevation of plasma FFAs results in cardiac lipid accumulation and whether this influences cardiac function negatively.Additional research objective: - to examine whether cardiac lipid content is…
This pilot study will investigate whether patients with both COPD and CHF who participated in a community based reactivation programme have a higher exercise capacity and a better health related quality of life after the programme in comparison with…
If certain combinations of micro RNA's that are predictive for recovery exist, they can be improtant for prognostic reasons and play a role in postponing device implantation. It may also help in choosing the right pharmaceutic regiment.