412 results
The extent of beneficial effects of AIT, including reverse remodeling and improved left ventricular function, exercise capacity, quality of life and level of physical activity, needs to be established in a phase II type clinical multicenter study…
ObjectiveThe overall goal of this project is to identify the specific genomic markers associated with severe anthracycline-induced cardiotoxicity to be able to identify high-risk patients. The specific objective of this proposal To validate and…
The aim of this study is to assess the effects of a small-group community based physical exercise programme on functional exercise capacity, activity rate and health-related quality of life in patients with chronic heart failure (CHF) and chronic…
In this study, we aim to establish whether temporary pacing is also effective in CTEPH patients who are not eligible for pulmonary endarterectomy, or those in whom pulmonary endarterectomy has failed. These severely symptomatic patients, for whom no…
With this study we want to investigate if the SPECT gated blood-pool can replace the planar gated blood-pool.
In patients who have undergone surgical repair of TOF, we aim to- assess the development of RV dimensions and function in relation to clinical outcome, in a time dependent manner,- identify, chracterize and quantify markers in blood samples, using…
The purpose of this study is to evaluate accuracy of Cardiac Output measurements by comparing the Cardiac Output calculated by Arterial Pressure based Cardiac Output (APCO) and by other well accepted indicator dilution techniques, as well by…
Primary:Comparing EPO induced proliferation, G2/G0 ratio, and apoptosis of UT7-EPO cells between anemic and non-anemic CHF patients. Secondary:1. Comparing the levels of several circulating inhibitory factors (TNF-alpha, TGF-Beta, Ac-SDKP, INF-gamma…
Monitoring the haemodynamic status during lung recruitment.
The first objective is to evaluate the safety of cetuximab in patients with scleroderma associated PAH. The secondary objective is to assess efficacy.
To study the feasiblity of cardiac MRI at 3T and the potential benefits of the intravascular contrast agent gadofosveset for studying and quantifiaction of heart function and -perfusion.
To improve the quality of care for children with End Stage Renal Disease by central registration and frequent intervision.
To compare sympathetic and haemostatic activity in rest and after rising in patients with chronic heart failure and healthy subjects, who will be randomly assigned to selective and nonselective beta-blockers. To analyse whether haplotypes of two…
Aim is to establish the relation between skin AGEs, measured as skin-autofluorescence, and diastolic dysfunction. Primary Research Questions1. Is there a relation between skin-autofluorescence and the severity of diastolic dysfunction in patients…
To establish the relation between myocardial, serum and skin AGE levels. To determine the quantitative AGE-levels in myocardial tissue
The proposed study aims to assess the technical reliability and user friendliness of the Intel platform in 25 patients who are in stable heart failure. Subsequently, the cost-efficacy of the technology will be assessed in 100 patients with a focus…
1. To determine if beta2-receptor polymorphisms influence the probability of recovery of heart failure.2. To determine possible other factors that influence the probability of recovery in our patient cohort.3. To determine the amount of LVEF…
The statistical analysis will evaluate the correlation of Baseline NGAL and BNP levels -alone and together - with the clinical outcomes of hart-failure (HF-related adverse clinical outcomesthrough Day 30 and Day 90. The cut-off and estimated…
The aim of the proposed study is to examine whether CRT has a positive effect on microvascular function and health outcomes, and whether psychological factors may moderate the effect of CRT on health outcomes.
1) To assess whether a correlation exist between the degree of pulmonary clearance of free radical positive white bloodcells and platelets and the degree of pulmonary congestion in congestive heart failure (CHF) patients2) To asses whether cardiac…