60 results
Primary:2. To investigate the prevalence of vulnerable plaques, i.e. plaques with intraplaque hemorrhage on MRI, in individuals with type 2 diabetes, impaired and normal glucose tolerance and a minimal plaque thickness of 2mm on ultrasonography. To…
The objective of this study is to demonstrate the influence of pectus excavatum on the anaerobic threshold during exercise. This could be an objective measurement of exercise intolerance. An objective measurement of exercise intolerance can later…
Verification of functional tests with the LoRRca, a next generation ektacytometer, on red blood cells of healthy individuals with or without comorbidities/risk factors.
To identify which component of hemodialysis is primarily involved in the reduction in myocardial blood flow.
The purpose of the study is to evaluate the usability of PatientCoach by patients with asthma and/ or COPD,hypertension and/or Diabetes Mellitus.
To perform a human study demonstrating a detailed analysis of electrical and mechanical activation under different cardiac pacing conditions and to describe the accompanying hemodynamic response.Objectives:To demonstrate non-invasive mapping…
The main objective of the study is to document cardiovascular dysfunction found in rheumatoid arthritis and gout patients using cardiac imaging techniques echocardiography and cardiac MRI.
To gain a better insight into the genetic factors that play a role in the etiology of the thoracic aortic aneurysm with the following specific aims:1. Study of specific geneitc factos that play a role in the pathogenesis of both syndromic and non-…
To assess the changes in cardiac function and the microcirculatory function in different thyroid states. We aim to identify how thyroid state affects changes in micro and macro hemodynamics.
The primary objective of this study is to assess the CV risk profile of Hindustanis without known diabetes mellitus (DM), hypertension, dyslipidemia or CV disease and evaluate the 10-year CV risk according to the Framingham risk score. Secondary…
1. To assess whether acute TRPV1 activation by capsaicin or ENaC down regulation by flavonoids modulate osmoregulation in healthy subjects2. To assess whether capsaicin and flavonoids affect blood pressure
The aim of this study is to develop and evaluate a shared care survivorship care plan (SCP) to follow-up patients with metastatic testicular cancer after completion of chemotherapy that resulted in complete remission.
1) To evaluate absolute myocardial blood flow and resistance over time in the acute and sub-acute phase of myocardial infarction2) To correlate these parameters to preservation of left ventricular function and long-term outcome.
Primary Objective: To assess whether ageing across body systems is accelerated by sub-optimal early life circumstances.Secondary Objective: To asses underlying mechanisms of the potential association between sub-optimal early life circumstances and…
The main objective in this study is to determine whether there is an effect of acute unloading of the left ventricle on the ECG, in particular the T-wave.
This pilot study is designed to determine the prevalence of female and male sexual dysfunction in a population of patients visiting outpatient cardiology clinics in the Netherlands. Furthermore we will determine whether patients visiting the…
The main objective is to investigate mechanical alternans and MTWA in TAVI patients to demonstrate a possible correlation between these two phenomena.
The general objective of the Doetinchem Cohort Study is to contribute to the answering of public health questions, now and in the future, by providing basic data on developments in lifestyle and health problems in the general Dutch population.
The main objective is to compare the electrophysiological differences and similarities between cardiomyocytes obtained by iPS and mature human cardiomyocytes.
We will test a new theoretical model that assumes that mental health status interacts with the genetic factors influencing sympathovagal balance and the pro-inflammatory state. The results will be published in scientific magazines, and/or presented…