386 results
The study objective is to evaluate the safety and efficacy of the Ablation Frontiers Cardiac Ablation System in the treatment of permanent atrial fibrillation.
Clinical evaluation of the Gen2 irrigated ablation catheter for the treatment of cardiac arrhythmias
The purpose of this study is to confirm the Gen2 irrigated Ablation Catheter will perform as expected based upon the observed rates in the literature for effectiveness and safety for similar CE marked and commercially available irrigated and non-…
The main objective of the study is to establish whether cardiac MIBG scintigraphy can be used as a risk-stratification tool in LQTS, Brs and CPVT.
This clinical study will evaluate the safety and performance of the Closure device to occlude the LAA during minimal invasive surgery. The objectives of the study are:• To evaluate the ability of the Cardioblate® Closure* device to occlude the LAA…
The aim of the present study is to evaluate whether there is an association between biomarkers (hs-CRP and BNP)
In this study we will study the incidence of QTc-interval prolongation when combinations of 2 or more QTc-prolonging drugs are prescribed. Also we will investigate if QTc-prolongation is more frequent in patients with higher drug plasma…
Primarily, this study aims to investigate (i) the feasibility and safety of a novel temporary epicardial pacing wire placement using two unipolar pacing electrodes embedded in a gelatin sponge and (ii) the stability of electrical performance of the…
Page number 6 of the study protocol5 STUDY OBJECTIVES5.1 PRIMARY OBJECTIVEThe primary objective is to show superiority in survival of the modified method with the LUCAS Chest Compression System, compared to the conventional manual resuscitation…
The objective of the pilotstudy is feasibility and safety.
The primary objective is to assess whether management of atrial fibrillation (AF) as well as the early optimization of cardiac resynchronization therapy (CRT) via Home Monitoring decreases mortality and morbidity compared to conventional treatment.
The aim of this study is to identify CHF patients who are most likely to benefit from ICD therapy by the use of clinical patient characteristics related to CHF combined with a measure of myocardial sympathetic integrity/activity. This will enable to…
The purpose of this Clinical Investigation Plan is to collect data on the safety and performance of the WiCS-LV system. It is designed to satisfy requirements for clinical data and post market clinical follow-up for the Active Implantable Medical…
To identify that fysical complaints fitting with atrial fibrillation, hyperthyroïdie, left atrial enlargment at ECG, left ventrikel hypertrophy at ECG, premature atrial complex (with heartbeat > 70 bpm) at ECG and cerebral ischemic attacks in…
To collect information of 1000 patients per coumarin (acenocoumarol and phenprocoumon) to investigate the impact of height and weight on the dose needed. The database will also contain other information of the patient, like age, gender and genotypes…
The primary objective is to establish whether patients are at increased risk for VT/VF during inflammation. The secondary objective is to establish whether increased risk during inflammation is mediated by hyperthermia and inflammatory cytokines.…
The primary objective is to show superiority in survival of the modified method with the LUCAS Chest Compression System, compared to the conventional manual resuscitation method in patients suffering from witnessed In-hospital cardiac arrest Primary…
Reduction of ICD/CRT-D follow-up by telemonitoring in a feasible way.
To determine the impact of catheter ablation on the left atrium by visualizing scar tissue in the left atrium, using delayed enhancement MRI, and to correlate this to possible changes in left atrial size and function following catheter ablation.
Primary efficacy objective: to test that patients with permanent or persistent AF and concomitant diseases requiring open heart surgery will be free of AF when treated with the Cardioblate Surgical Ablation System using a modified Maze III procedure…
To document a single centre learning curve to use 3D ATG overlay with catheter position tagging to assist atrial fibrillation ablation procedures.To compare use of 3D ATG overlay and the tagging tool contemporary mapping/localisation tools (Carto or…