89 results
To examine the effect of BCG as an adjuvant on DTP vaccination, and to investigate the non-specific training effects of BCG and DTP, alone and in combination, on the innate immune system.
Are Alphabodies against IL23 effecive in the transplant model of psoriasis
Primary: To provide insight in the prevalence of diagnosed cases of IgG-subclass and/or antipolysaccharide antibodydeficiency in Dutch children. Secondary: To provide insight in the diagnostic process, the clinical presentation, the therapies used…
Determine whether the prevalence of allergic sensitilization, defined as at least one allergen specific IgE with a concentration of >= 0,35 kU/l, is lower in people with than without DS. Analyse whether this prevalene is depending on age, how…
To define differences in the molecular composition of human milk extracellular vesicles between allergic and non-allergic mothers. Additionally, other differences in human milk composition will be analyzed (cellularity, nutrient content,…
Our purpose is to establish whether the frequently observed absence of tumor regression in the presence of infiltrating T lymphocytes is due to a lack of T cell effector function or due to an inhibitory influence of the tumor microenvironment on T…
objective
To collect and store a serum sample of each patient that is referred to the Leiden University Medical Centre for evaluation of neuropsychiatric symptoms in SLE.
Client wishes to see if HPP-A is active in the transplant model of psoriasis
Clarifying the qualitative and quantitative aspects of the T cell response targeting and controlling polyomavirus BKV.
In this study we want to apply heavy water labelling to investigate how ageing affects the dynamics of different leukocyte populations.The main objectives of this study are:(A) to get more insight in the dynamics of an ageing immune system, in order…
To evaluate the reproducibility of the SvdH score (BE and JSN of one hand) of radiographs taken with a mould compared to conventionally acquired images.
Is CMPX-2030 effective in the transplant model of psoriasis
In this study we intend to give the label "deuterium" to individuals as heavy water, to determine the turnover parameters of diverse leukocyte populations in health (young adults, healthy seniors of 60 years and older, healthy individuals…
Measuring the stability (and thereby half-life) of TRECs.
The main aim of the proposed study is to 1) assess the habitual consumption of raw cow*s milk among a large population of adult dairy farmers; 2) assess the association between raw cow*s milk consumption and inflammation-related, auto-immune and…
Primary Objective: The primary objective is to analyse the humoral and cellular immune response to influenza vaccination in PHTS individuals.• Is the immune response to seasonal influenza vaccinations impaired in PHTS?• Do characteristics in humoral…
Consuming Migo pear without getting allergic symptoms.
The main objective is to investigate the association between walking fatigability during the 6 minute walking test (6MWT) and walking economy in pwMS who are able to walk independently. Secondary objectives are to investigate the role of I. walking…
To study patients with clinically suspect arthralgia in order to 1) develop diagnostic/prognostic markers (a. markers of systemic and b. local inflammation as well as c. autoantibodies) for the development of RA 2) to improve the mechanistic…