336 results
1) Formulating a dose regimen for intravenous infusion of amoxicillin 1) More insight into the pharmacokinetics of amoxicillin in children of ages making more specific dosing possible.
To study the immune response to vaccination with influenza virus vaccine, conjugated Hib and pneumococcal vaccine after treatment with rituximab in association with the reconstitution of immune function (in terms of amount of B-cells and…
Dividing the study population in four categories (oncological patients, critically ill patients admitted to intensive care, neonates and other children) answers to the following questions are sought:- which initial dosage regimen for vancomycin…
This study aims to identify qualitative and quantitative differences in innate, cellular and humoral immune response between persistent, intermittent and noncarriers of S. aureus.
To determine the effect of probiotics (microbial food supplements) on acquisition rates and colonization prevalence of CC17 ARE in two wards where ARE-colonization is endemic.
1. To decrease the proportion of infants treated with antibiotics for > 48 - 72 hours with possible or unlikely infection. 2. To reduce the duration of antibiotic therapy
1.) Is the gut flora of the healthy infant on day 3, day 7 and day 28 originally from the mother or the environment?2.) Is the process of colonizing in healthy term infants dependent on the mode of delivery?3.) Does breast milk contain bacteria and…
The study the influence of two different inhalationflow manoeuvres on the lungdeposition in patients with cystic fibrosis categorized to patientgroups varying in FEV1 longfunction value and age.
To study the effect of ethanol lock therapy on the cure rate of catheter-related infections (CRIs) and on the incidence of (CRI related) venous thrombosis in total parenteral nutrition (TPN) patients with tunneled central venous catheters older than…
The objective of this study is to identify determinants, to determine the transmissibility and to determine the burden of disease of NT-MRSA and CA-MRSA carriage compared to other typeable MRSA strains in the community.
To study the effect of ethanol lock therapy on the cure rate of catheter-related infections (CRIs) and on the incidence of (CRI related) venous thrombosis in pediatric total parenteral nutrition (TPN) patients with tunneled central venous catheters…
What is the proportion of STI outpatient clinic visitors with a persistent colonisation of chlamydia in the pharynx up until 3 weeks after the first diagnosis based on a NAAT positive chlamydia pharyngeal swab.
Objectives: 1) Describe the course of muscle SrO2 in patients with severe sepsis in relation to outcome and severity of disease 2) Describe the relationship between muscle SrO2 and serum lactate, SvO2, DO2 and VO23) Describe the course of cerebral…
Primary objectiveTo determine the development of the cellular immune response (plasma B cells and memory B-cells), immediately before and after the booster of the 3+1 Prevenar® vaccination schedule at 11 months of age and before and after the…
This prospective randomised study has the primary objective to prove a reduction of postoperative wound infections after direct preoperative use of a microbial sealant in the form of Integuseal for vascular procedures on lower extremities. We aim at…
Overall aim: to determine the extent and risk factors for farm-based and individual acquisition of Coxiella burnetii infections on ruminant farms to improve veterinary, occupational and public health by providing leads for primary (reduce…
To examine whether the use of systemically administered antibiotics in therapy resistant Lichen Sclerosus leads to:- Relief of symptoms- Improvement of clinical picture- Improvement of histological abnormalities- Effect on quality of life-…
Primary objective: To determine the dynamics of MRSA carriage in persons working on or living at pig and veal farms.Secondary objectives: To determine the amount of disease associated with carriage of MRSA-CC398. To determine the role of exposure to…
Primary aimTo apply the CGT (intravenously and arterial sampling) in patient with multiple organ failure for the assessment of enterocyte function as a measure for intestinal (small bowel) barrier function.Secondary aimsTo compare the CGT with other…
The objective of this study is to obtain whole blood from patients with S. aureus infections and/or patients whose wounds are colonized by S. aureus for in vitro development of human monoclonal antibodies against S. aureus.