19 results
Primary Objective:Pilot study: Selection of the titanium derivatives which are capable of penetrating the skin, and thus can be used in the full study as patch test materials.Full study: To compare the results of three different diagnostic tests…
The primary objective is to compare the haemostatic effect of VHA-guided transfusion strategy versus optimized CCT guided transfusion strategy in haemorrhaging trauma patients. The secondary objectives of the study are to determine the effects of…
To establish the incidence and consequences (impairments op body functions, limitations in participation) of traumatic brain injury in children and youth in a region of The Netherlands as well as the incidence of the same symptoms in a group of…
The Activation of Coagulation and Inflammation in Trauma (ACIT) study is designed to identify the clinically significant mechanisms and pathways by which inflammation and coagulation are activated immediately following major trauma, and how these…
The aim of this study is to determine the immediate effects of oral alcohol consumption in healthy volunteers on gut wall integrity as measured by Intestinal Fatty Acid Binding Protein (I-FABP) and Lipopolysaccharide Binding Protein (LBP) These…
In this pilot study experience will be obtained in diagnosing POCD and its risk factors, in elderly surgical cancer patients.
First objective; to document the existence and to categorize vocal fold pathology after short term intubation and to study voice related patient complaints after short term intubation. Second and third objective; to study the pattern/type of injury…
The study objectives are to measure the impact of swimming in chlorinated water on the upper and lower airways of children with and without *doctors diagnosed asthma* by means of the following methods: 1.Tympanometry after otoscopy 2.Airway…
the aim of the proposed study is to assess the load of anatomical hip, knee and ankle joints in people that use one leg prosthesis for sprinting. The loading of both ipsi- (if present) and contralateral joints will be assessed.
To analyse sensibility of the stump in adults with an acquired upper extremity amputation and compare the sensibility with the corresponding part of the contralateral arm and the contralateral fingers. Sensibility of the non-affected arm and fingers…
To test the hypothesis stated above, we propose to study the dose-response relationship between various chemostimulants and PMN functions of major trauma patients and patients undergoing major surgery in vitro, both early after the initial trauma or…
The objective of this study is to prove that chronic post-sternotomy pain is not a local painproblem, but part of a general painsyndrom.Our hypothesis is twofold:1. The investigated painsymptoms are of more frequently occurrence in the pain-sample…
The current study aims to gain better insight into the pathophysiology of the aberrant inflammatory response in CRPS. The evaluation of the role of pro-inflammatory and anti-inflammatory mediators in response to a microtrauma may generate important…
The Activation of Coagulation and Inflammation in Trauma (ACIT) study is designed to identify the clinically significant mechanisms and pathways by which inflammation and coagulation are activated immediately following major trauma, and how these…
Primary Objective: to determine the pathophysiology of post-extubation dysphagia in ICU patients after prolonged endotracheal intubation using simultaneously recorded flexible endoscopic evaluation of swallowing (FEES), high resolution impedance…
The primary objective is to investigate the differences in mentalizing abilities between outpatients with chronic pain and a control group, consisting of outpatients with painful acute injuries or painful somatically explained conditions. The…
Primary Objective: To investigate the effect on the distention of the ONSD while using lidocaine 1,5 mg/kg IV during endotracheal intubation versus placebo. Secondary Objectives: The secondary objective of this study is to investigate the effect…
By means of this study we want to determine how many victims of sexual violence, who seek help within 72 hours at the CSG Gelderland Zuid-Midden (CSG-GZM), have alcohol and/or drugs in their urine, voluntarily or involuntarily. To make it clear how…
1. To determine risk factors for BIA-ALCL in women with silicone breast implants. The associations between demographic-, reproductive- and lifestyle characteristics and BIA-ALCL risk among women with breast implants will be investigated. Furthermore…