54 results
The primary objective is to study if non-diabetic patients with biopsy-proven NASH have higher hepatic FDG-uptake as compared to non-diabetic patients with biopsy-proven non-inflammatory steatosis?Secondary Objectives are (1) to study the…
To assess the diagnostic accuracy of MR Elastography in detecting and monitoring different degrees of liver fibrosis compared to FibroScan and histopathology in patients with suspected chronic viral liver disease and non-alcoholic fatty liver…
Primary Objective: * The feasibility of combining MRE and 1H-MRS in NAFLD to distinguish simple steatosis from NASH. Secondary Objective(s): * The influence of steatosis on MRE measurement* The influence of inflammation on MRE measurement
To study the effect of peginterferon alpha and ribavirin on spermatozoa
Validation and quantification of 3.0 Tesla 1H *MRS for the assessment of hepatic steatosis in patients with non alcoholic fatty liver disease and patients chronically infected with hepatitis C. Is there a close correlation between the 1H *MRS…
Primary Objective:Validate the accuracy of:· MR Flow mapping in measuring PPG in patients with GoreTex®-covered TIPS as compared to the gold standard, portography.· MRA for establishing TIPS patency as compared to Doppler US and using invasive…
To establish platelet function during orthotopic liver transplantation.
The aim of this study is to validate a protocol for ultrasonographic hepatic fat assessment, by means of Magnetic Resonance Imaging technique (MRI) as gold standard.
Validation of pre-operative H1-MRS at 3.0 Tesla for assessment of hepatic steatosis as a risk factor for postoperative morbidity and mortality after hepatectomy. Is there a close correlation between the 1H -MRS measurement of fat and the…
In the present study, this cohort of patients will be examined once by means of MR imaging. We expect to be able to determine if, and how frequently, these patients will have to examined by means of follow-up MR imaging in the future. The final…
To investigate peripheral circulation in the hyperdynamic circulation of cirrhotic patients and its correlation with the Child-Pugh score.
The primary aim of the study is to assess the prevalence of MDRO carriage in patients undergoing ERCPs. This will be performed in four different countries with expected significantly different prevalence rates of MDRO carriage, namely: India, United…
To compare retrospectively reconstructed, radially sampled contrast-enhanced MR images of the liver with conventionally acquired contrast-enhanced MR images of the liver in terms of Quality of enhancement (QE), overall image quality (IQ), liver edge…
Identify markers predicting progression of fibrosis in treated autoimmune hepatitis patients
Primary Objective: Assess the ability of MRCP+ and LMS to detect change in total biliary volume and cT1 value, 8 weeks after endoscopic treatment of dominant strictures, by a clinical decision rule.Secondary Objective(s): Assess natural course of…
The primary study objective is to evaluate the correlation of the calculated portosystemic pressure gradient (PPG) obtained by direct portal and hepatic pressure measurements with the EchoTip® systemic Pressure Gradient (EchoTip® InsightTM) and…
1) determine the percentage of children with probable significant fibrosis (F>=2) using FibroScan®, when screening children based on the NASPGHAN 2017 guideline.2) determine the cost-effectiveness of screening for NAFLD when following the…
Primary objective • In this study we will investigate whether biochemical imaging of change (Δ, figure 1) in the metabolic phospholipid ratios of PME and PDE between baseline and after 2 weeks of therapy are predictive for progression free survival…
The study aims to determine the feasibility and diagnostic accuracy of quantitative Magnetic Resonance Imaging (MRI) techniques for determining the presence of portal hypertension in patients with severe liver disease. The secondary objectives are…
The primary objective is to develop and validate non-invasive portal pressure measurement by MRI in patients with end-stage liverdisease (ESLD).