53 results
To assess the involvement of a specific genetic risk allele on oxidative stress induced by neutrophils in relation to H. pylori infection.
The aim of this study is to demonstrate which is the most effective operation for neonates with necrotizing enterocolitis (NEC): intestinal resection with stoma formation or intestinal resection with primary anastomosis.
Primary Objective: To determine the sensitivity and specificity of MRI in a consecutive series of adult patients suspected for acute appendicitisSecondary Objective(s): Is MRI of additional value in adult patients with inconclusive US? And is…
To determine the prevalence of T. whipplei in duodenum and colon in a random population of patients whom will undergo an endoscopy at the VUmc
1.What are ulcerative colitis patients* understanding of their risk of colon cancer and the benefit of colonoscopy?2. What is ulcerative colitis patients* threshold of cancer risk before accepting colectomy in the setting of dysplasia?3. What are…
1.) Is the gut flora of the healthy infant on day 3, day 7 and day 28 originally from the mother or the environment?2.) Is the process of colonizing in healthy term infants dependent on the mode of delivery?3.) Does breast milk contain bacteria and…
To determine the value of MRI in a consecutive series of pediatric patients suspected for acute appendicitis
We want to study whether consumption of Lactobacillus acidophilus NCFM* can improve the resistance of humans to intestinal ETEC infection. An important parameter of intestinal resistance is the so-called colonization resistance. The colonization…
The main objective of this study is to investigate the effect of probiotics on the sequels of ETEC administration as intestinal permeability, inflammation and clinical signs as total faecal output, relative faecal dry weight and mucin excretion in…
With this study we will investiagate the superiority of fecal clysma therapy (n=34 patients) above conventional therapy with the antibiotic vancomycin (n=34 patients) or bowellavage with conventional antibiotic therapy (n=34 patients).
This study aims to gain insight into the effect of inflammatory factors on bone metabolism. For this purpose we formulated the following research questions:1. Which circulating inflammatory factors play a central role in the pathogenesis of general…
The goal of this trial is to confirm that eradication rates obtained with Pylera are compatible to those obtained with the current European gols standard, OAC 7 days. This trial will constitute a pivotal trial leading eventually to approval of…
In case of food- or water related outbreaks of bacterial gastroenteritis, the regular research of Municipal Health Services (GGD) and the Food and Consumer Product Safety Authority (VWA) aims at control of the outbreak.The aim of this project is to…
To determine the usefulness of multiplex real-time pcr to detect asymptomatic parasitic infections in travellers returning from the tropics.
Primary Objective: In the CORAL study we want to determine whether increasing the inoculation dose of diarrhoeagenic E. coli to 5*10^10 CFU and addition of a second challenge 1*10^10 CFU will result in an increased effect-size and duration of…
Primary objective:To determine the incidence of Clostridium difficile infection (CDI) in hospitalized patients aged * 50 years old and receiving oral or intravenous fluoroquinolones, cephalosporins, penicillins + beta-lactamase inhibitors,…
Primary: To determine fecal calprotectin in patients treated with checkpoint inhibitors. Secondary: To describe endoscopic and histologic findings in patients with symptoms that may indicate colitis.To study cytokine production profiles of the…
Primary:* To assess the efficacy of 2 x 1 mg/d budesonide effervescent tablets vs. placebo for the induction of clinico-pathological remission in adult patients with active eosinophilic esophagitis (EoE).Secondary:* To study safety and tolerability…
To prove that sustained clinical remission can be maintained at week 14 with a new dietary strategy that involves only 2 weeks of EEN with Modulen and 22 weeks of an exclusion diet involving selected table foods. We hypothesize that use of EEN for…
To evaluate the accuracy of H. pylori determination in FIT