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Plastic or Metal Stents for Primary or Recurrent Inoperable Malignant Extrahepatic Biliary Obstruction

To define indications for recently developed, but more expensive, self-expanding metal stents (SEMS) versus cheaper plastic stents in patients with primary or recurrent inoperable malignant extrahepatic common bile duct (CBD) obstruction, based on…

Assessment of trans-intestinal cholesterol excretion in patients with total biliary obstruction
(TICE-PTC)

To establish the presence of direct trans-intestinal cholesterol excretion (TICE) in humans by faecal recovery of i.v. administered 13C-cholesterol in patients with a total biliary obstruction. This is a so-called proof-of-concept study.

Comparing the effects of a new method to prevent constipation according to the usual method to prevent and to treat constipation bij patients lying in the hospital with a neurological disease.

The effectivity of a standard preventing constipation and treatment list, designed by the hospital nutritionteam, will show that neurological patients during their stay in the hospital develop less constipation.