30 results
The current study is a continuation of the cohort 5-8 years post-diagnosis and aims to evaluate:1.The course of the nutritional status, and the related factors and consequences of malnutrition in survivors of childhood cancer until 5-8 years post-…
The aim of this study is to validate known, and identify novel allelic variants which may play a role in the risk of cisplatin-induced ototoxicity in a substantial international cohort of children diagnosed with cancer.
We will investigate whether the Respecting Choices program will improve communication between patients and healthcare professionals, will improve the QOL and wellbeing of patients and their relatives, will reduce futile treatments and unnecessary…
We aim to test the effectiveness of a patient-targeted preparatory tool (*Gesprekswijzer*) and an oncologist-targeted communication skills training to enhance shared decision making in consultations about palliative systemic treatment. The primary…
The aim of this international field study is to test the scale structure, reliability, responsiveness to change and validity of the EORTC SHQ-C22 in patients with different cancer diagnoses, at different stages of disease, and with different…
The primary objective of this study is to determine the impact of a diagnosis and type of treatment of cancer, ageing and their interaction on wellbeing of older cancer patients. Furthermore, we aim to determine the different psychosocial…
To gain insight in mechanisms of case management and in succesful and less succesful aspects of case management in individual patient care. This leads to knowledge of potential added value of case management to regular care and (if there is added…
Primary objective: To determine the feasibility, perceived usefulness, and patients' satisfaction regarding occupational rehabilitation during chemotherapy in a clinical setting, consisting of counseling by an occupational physician, and an…
The aim of this pilot study is to provide insight into the technical functioning, usability, acceptability, comprehensiveness, and feasibility of the telemonitoring intervention and care organisation, for both patients as well as participating…
This quantitative research project was preceded by a qualitative study (Sexuality in people with a limb amputation and their partner: a qualitative study; METc 2010/179). The aims of the current study are to explore:- which sexual problems occur in…
The aim of this study is to evaluate the effect of the intervention regarding pain intensity and quality of life as compared to care as usual. Secondary outcomes of the effect evaluation are self-efficacy, knowledge, depression and anxiety, and…
Primary objectivesIn all patients included in the studyTo asses whether:- MP-TF activity and MP phenotype is associated with specific types of malignancy.- MP-TF activity and MP phenotype predicts for development of thrombosis.- MP-TF activity and…
The objective of this study is to determine the effectiveness of receiving a multidisciplinary protocolized patient-tailored treatment of physical symptoms (PPT) in combination with structurally monitoring of reported symptoms (the intervention) on…
In the past there has been little attention for quality of life, of which sexuality is an important part, in both scientific research and in clinical practice. Nowadays things are changing and talking and thinking about the sexual functioning and…
Identifying factors that are involved in the way social support is experienced by the patient when confronted with cancer.
This study will focus on the nutritional problems described above of children treated for cancer. The study will describe: the nutritional state during treatment, the determinants affecting the nutritional intake and the impact of nutritional…
The main objective of this project will be to test the hypothesis that SNP profiles can improve the performance of predictive models for the most frequently reported late RISE, i.e. dysphagia, in HNC patients after curative (CH) RT. Secondary…
To investigate whether a tailored physical activity program that starts early (during curative chemotherapy with cardiovascular toxic potential) is superior in terms of reducing long-term cancer-treatment-related metabolic syndrome and…
Primary Objective: Main aim of the study is to investigate in detail the differences in gene expression, body composition, muscle function and muscle metabolism in colon cancer patients compared to controls. Secondary objectives:Secondary aim of the…
Primary Objectives• To evaluate in vivo complement activation after first-time treatment with paclitaxel, liposomal doxorubicin (Caelyx) or other complement-reactogenic compounds• To evaluate ex vivo complement activation after incubation of predose…