80 results
To evaluate whether (changes in) systemic CysC-concentration can be used as a marker for improvement of the renal function in critically ill patients while treated with HF.
Objective: Evaluation of the supposed correlation between increased serum and urine NGAL levels (> 350 ng/ml) and significant increases in serum creatinine levels in adult ICU patients compared to preclinical levels
Primary objective: Is there a similar circadian rhythm of epo and melatonin in patients with the same degrees of renal insufficiency?Primary Objective: Is there a similar circadian rhythm of epo and melatonin in patients with various degree of renal…
We would like to investigate the role of CE-US with Sonovue (Bracco) in patients with RCC. Our primary objective is to establish the diagnostic accuracy of CE-US in renal masses suspicious for RCC.Our secondary objective is to establish the pattern…
The goal of this study is to answer the following questions:1. Is the chance of detecting mtDNA mutations in blood or urine sediment as high as in a (much more invasive) skeletal muscle biopsy sample?2. What is the prevalence of renal failure in…
The aim of this project is to enhance transplantation prospects of highly sensitized patients who are waiting for a long time for a suitable kidney graft. Despite their inclusion in the Acceptable Mismatch (AM) program (initiated in The Netherlands…
To evaluate whether (changes in) serum CysC concentration can be used as a marker of renal function in a large cohort of critically ill patients, and to describe the kinetics of CysC in these patients.
Based on this background information and our preliminary data in this project we aim to perform longitudinal study in cystinosis patients to correlate clinical course under cysteamine therapy and 1) Markers of macrophage activation in patients…
To study the effect of renal clearance on the biological variation and the circadian rhythm of cardiac troponin.
In the current study, we intend to study the diagnostic accuracy of promising urine biomarkers for early detection of acute kidney injury in patients undergoing major general surgery. The study is designed to validate earlier findings in a large…
To make MRI suitable for an MRI-only workflow for magnetic resonance (MR)-guided (MR-linac) stereotactic radiotherapy for localized RCC. The objective of the current study will be MRI-sequence optimisation. Sequences will be optimized for MR-based…
To study the clinical value of pressure and flow assessment for predicting treatment response to PTRA and validate the pressure gradient assessment by CFD in patients with available CT angiography.
Primary objective: To determine the prevalence of AKI in critically ill children based on clearance of iohexol.Secondary objectives:1. To determine the prevalence of AKI in critically ill children using serum creatinine, creatinine clearance,…
2.1 Primary objectiveThe primary objective is to determine whether perirenal adipose tissue thickness is increased in patients with HFpEF compared with age, sex and BMI-matched healthy controls2.2 Secondary objectivesThe secondary objectives are to…
Through the utilization of fMRI and DUS we aim to illustrate the physiological change a kidney graft undergoes during a transplantation trajectory from donor to recipient. Secondarily, we intend to establish a baseline reference for normal…
Primary Objective: the relation between the occurrence of CSA-AKI and the duration of peri-operative low mitoPO2 measurements (<20 mmHg). Secondary Objective:- To study the relationship between the occurrence of postoperative cognitive…
The aim of this study is to establish reference values for plasma oxalate and plasma glycolate levels in patients with chronic kidney insufficiency. Values in patients with PH and secondary hyperoxaluria will be compared to values measured in…
The aim is to see whether intradialytic parenteral nutrition is an efective treatment against the loss of muscle mass
The aim of the current study is two-folded. The primary aim is to assess the impact of NMP on the incidence of PNF/DGF. Secondly, we investigate the association between microcirculation and oxyhaemoglobin during NMP as measured with the MoorO2Flo…
The primary objective of this study is to assess the dynamic range of renal pressure and flow velocity under exercise induced minimal flow and dopamine induced hyperemia. Secondary objectives are to assess intra-individual variations in the range of…