37 results
To monitor the effect of the free plate technique in Baerveldt implant surgery on the postoperative eye motility.
The purpose of this study is to collect additional safety and effectiveness of the InnFocus MicroShunt (MIDI Arrow) in subjects suffering from primary open angle glaucoma that are inadequately controlled on maximum tolerated medical therapy with…
The primary objective is to study glaucomatous structural brain changes in a longitudinal manner, and how it relates to visual functional loss and glaucomatous retinal changes over time.
The primary objective is the degree of IOP lowering after trabeculectomy with adjuvant Ologen® implantation, in comparison to trabeculectomy with mitomycin-C. Secondary objectives are peroperative and postoperative complications, and postoperative…
Demonstrate that compared to trabeculectomy, at 12 months follow-up:- a Baerveldt implant is not inferior with respect to IOP and- a Baerveldt implant is superior with respect to failure.
The purpose of this study is to expand knowledge of the IVANTIS Hydrus Implant's ability to decrease intraocular pressure (the pressure in the eye).
The objective of this study is to demonstrate the safety and effectiveness of the Hydrus Aqueous Implant for lowering IOP in patients with primary open-angle glaucoma (POAG) who are undergoing concurrent cataract surgery.
The purpose of this research study is to demonstrate that the fixed combination brinz/brim used twice daily has a similar effect (both in terms of reduction of the eye pressure and possible side effects) as brinzolamide and brimonidine used twice…
The objective of this study is to compare the efficacy and safety of the preservative-free fixed-dose combination of tafluprost 0.0015% and timolol 0.5% eye drops to those of tafluprost 0.0015% and timolol 0.5% eye drops given as individual…
A new formulation of DuoTrav® eye drops, called DuoTrav APS, in which, the preservative (BAC) has been replaced by a new preservative called POLYQUAD has been developed. POLYQUAD is expected to be better tolerated in the eye, especially for the…
To demonstrate that externally induced increases in epipalpebral pressure (EPP) relate to clinically significant increases in IOP, and to determine posture dependency of EPP. To determine the effects of protective goggles on EPP under these…
The primary objective of this study is to demonstrate that the IOP-lowering efficacy of Travoprost Ophthalmic Solution, 0.004% (preserved with POLYQUAD) is noninferior to Timolol Ophthalmic Solution (0.5% or 0.25%) in pediatric glaucoma patients.
In the present study, we will investigate if a monocular visual field defect - due to primary open angle glaucoma - influences the anatomical integrity of the visual pathways.
Part 1: To determine the effectiveness of self-instillation of fluorescein drops by means of the combined E-Box/Xal-Ease device. Part 2: To determine patient satisfaction of the two administration procedures, i.e. Xal-Ease versus E-Box/Xal-Ease.
The purpose of this clinical trial is to evaluate the clinical performance of the PACT procedure in lowering intra-ocular pressure in subjects with elevated intra-ocular pressure, as a function of glaucoma or ocular hypertension.
To demonstrate that externally induced increases in subpalpebral pressure (SPP) relate to clinically significant increases in IOP, and to determine posture dependency of SPP. To determine the effects of protective goggles on SPP under these…
To study the effect on intraocular pressure in patients using the Travalert dosing aid with or without the additional use of the Eyot and with of without additional patient education.
To determine the effect of tube position in the anterior chamber on the corneal endothelium.
The objective of this project is to aid in deciding on the use of the MicroShunt in glaucoma surgery by assessing its efficacy and cost-effectiveness in patients with primary open-angle glaucoma (POAG), pigment dispersion syndrome or ocular…
The aim of this study was to test these biomarkers of NO in glaucoma patients both with and without tinnitus. The objective was also to replicate findings from a previous study performed in Amsterdam, a collaboration between our research group and…