130 results
To draw definite conclusions about the effectiveness of omega-3 PUFA supplementation in anorexia nervosa patients a double-blinded, placebo-controlled randomized controlled trial (RCT) with a substantial sample size should be conducted. Prior to…
Although electroconvulsive therapy (ECT) is an effective treatment for depression, preventing relapse after successful ECT remains a major challenge. In the PRASED-study we evaluate the effectiveness of three strategies to reduce relapse: an…
The goal of this study is to gain insight into the eating behaviors of women with an eating disorder (ED) and comorbid autism spectrum disorder (ASD). By comparing this group to two other groups (women with an ED but without ASD and women with an…
The aim is to study the effectivity of a brief, intensive, outpatient group treatment (ERP) for youths with chronic tic disorders/Tourette Syndrome (TS), to improve treatment outcome, daily functioning/quality of life and treatment satisfaction. If…
The objective of this study is to investigate if VR as a pre-module improves the willingness to start with exposure in vivo.
The primary objective is to determine the efficacy of methylphenidate on ADHD symptoms in Smith Magenis syndrome.The secondary objectives include the efficacy of methylphenidate on emotion dysregulation and specific goals that are important to the…
The aim of this study is to validate EEG prediction markers of antipsychotic treatment outcome in patients with psychosis. *
Our primary objective is to determine the effect of ICU-VR-F on symptoms of depression, anxiety and PTSD, and the health-related quality of life (HRQoL) in family members of ICU patients. The secondary objective is to determine the effect of ICU-VR-…
This is the first study to combine both objective and subjective daily measures (EMA and actigraphy) to assess fluctuations in suicidal ideation, in real time and in natural settings. The aims of the study are (1) to examine how momentary risk and…
This study has been transitioned to CTIS with ID 2023-506873-36-00 check the CTIS register for the current data. The primary objective of this study is: Part 1: To evaluate the efficacy of AL001 compared with placebo as measured by CDR® plus NACC…
This study has been transitioned to CTIS with ID 2024-516427-13-00 check the CTIS register for the current data. Substudy A: The primary objective will be to investigate the relationships between HPA axis dysfunction, early life adversity (ELA), and…
We aim to provide a neurocognitive account of communicative disabilities in patients with autism spectrum disorder (ASD), focussing on shared representations of a communicative context. We expect that ASD patients show impaired shared…
Primary Objective: Investigate whether EMDR Flash Forward is an effective intervention to process the mental images of worst case scenarios that occur in paranoid delusions, in order to decreases the preoccupation with the delusion.Secondary…
Objective: We aim to optimize the application of an existing drug, metformin, for a new indication, AiWG, by showing that metformin in combination with lifestyle interventions reduces AiWG compared to placebo in combination with lifestyle…
To explore the prevalence of mental disability in patients with personality disordersTo explore the predictive value of the SCIL for mental disability in this populationTo explore the predictive value of the adaptive functioning in patients with…
The objective is to examine how working memory functioning in children with ADHD and/or ASD as measured with the Lion game and the Monkey is influenced by context and to assess the diagnostic utility and ecological validity of the Lion and Monkey…
The current study aims to elucidate neural correlates of pain processing and dissociative analgesia in PTSD. To this end, we want to replicate the pilot study by Mickleborough et al., (2011) and test the functional pain processing protocol with…
The objective of the current study is to eveluate whether EMDR is effective in reducing PD symptoms.
Primary objective: To investigate changes in biological and psychological markers for patients with an unipolar depressive disorder during treatment.. In specific, we will study the relationship between depressive symptomatology with changes in…
The main goal is to test whether individuals with a panic disorder diagnosis differ in the level of fear generalization compared to matched controls. This would be a direct replication of the seminal study by Lissek et al. (2010).