60 results
Primary objective: Does a personalised behaviour intervention comprising of targeted in depth screening on mental health problems and drug use increase help seeking behaviour among MSM who are at high risk for STIs and HIV. Secondary objectives:…
Primary Objective: To identify dropout rates at all stages of fertility care at the fertility centres of Isala in Zwolle, Erasmus MC in Rotterdam, Reinier de Graaf group in Voorburg, Elisabeth Twee Steden in Tilburg, the St Antonius Ziekenhuis in…
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To investigate acute effects of a single 40 mg dose hydrocortisone, compared with placebo, on stress and various aspects of attention and other cognitive processing of emotionally relevant stimuli in healthy anxious young females. The main question…
The main objective of this study is to determine the role of freeze-fight-flight reactions in the development and maintenance of PTSD symptomatology.
Objective: Primarily, the objective of this study is to assess the role of serotonergic and dopaminergic polymorphisms in fear conditioning. Secondary, we will investigate additional cannabinergic and corticotropinergic polymorphisms in fear-…
This study addresses the following three questions:1. How do fear memories change over time?2. How is the context of fear coded in the brain?3. How can the process of excessive strengthening of fear memory be disrupted
The main objective for this proposal is to investigate the neurophysiology of BDD, and compare irregularities of BDD neurophysiology with OCD neurophysiology.
The key objectives of the study are:(1) to assess the effect on the quality of client-caregiver interaction by a treatment protocol designed around a specially developed mobile device. Moreover, attention will also be given to differentiation among…
The present study aims at testing fear conditioning in healthy volunteers. We want to examine whether behavioural results are comparable to the results reported in the literature and if they are suitable for use in future studies with (…
The closer examination of acute effects of a single administration cortisol. compared to placebo, on different aspects of attention and other cognitive processing of emotionally relevant stimuli in healthy young men. The central question is what…
The aim is to examine whether care and treatment guided by structural psychosocial screening leads to a better quality of life and greater patient satisfaction than usual care alone in patients with lung cancer.
Several meta-analyses have shown that guided self-help through the internet is effective in treating anxiety disorders. However, the cost-effectiveness of guided self-help in regular mental health care has not been studied yet. In the current…
The aim of this proposal is to investigate the potential use and value of experienced utility, as measured by the ESM and the DRM, in the economic evaluation of health care.Research question:1. What are the differences between the utilities measured…
What is the prevalence of depression and anxiety in children with asthma. Is this more frequent in asthma than in other chronic conditions like diabetes and Coelikie? And how compares this to healthy children in the same phase of life?
To test the impact of the GABAergic system on fear responses by assessing the effect of genetically determined GABA concentrations in the amygdala on psychophysiological and neural correlates of fear learning and fear extinction.
To explore the effect of stress on the neural correlates of emotion regulation, we will combine sophisticated behavioural tasks in a functional magnetic resonance imaging (fMRI) setting with a well-established stress-induction procedure.
First, we want to examine whether a CBM training aimed at inducing positive appraisal style (positive CBM-app) can alter dysfunctional appraisal styles in PTSD patients. Second, we want to examine whether this CBM-app training has an effect on PTSD…
The aim of the study is to examine the well-being of the children involved in fatal partner violence, in terms of post traumatic stress, comorbid psychopathology, mourning, daily functioning and quality of life. In addition, the aim is to…
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