48 results
This study addresses the following three questions:1. How do fear memories change over time?2. How is the context of fear coded in the brain?3. How can the process of excessive strengthening of fear memory be disrupted
The main objective for this proposal is to investigate the neurophysiology of BDD, and compare irregularities of BDD neurophysiology with OCD neurophysiology.
The major objective of this pilot study is to delineate SAD endophenotypes by investigating information processing characteristics, brain activity and connectivity, within the two key dimensions relevant to the SAD symptomatology: attention and…
Do trauma cues trigger more craving in individuals with substance dependency and PTSD in comparison with substance dependent individuals without PTSD? If so, is this effect trauma-specific or are SUD-patients with PTSD more sensitive to general…
The present study aims at testing fear conditioning in healthy volunteers. We want to examine whether behavioural results are comparable to the results reported in the literature and if they are suitable for use in future studies with (…
The closer examination of acute effects of a single administration cortisol. compared to placebo, on different aspects of attention and other cognitive processing of emotionally relevant stimuli in healthy young men. The central question is what…
The key objectives of the study are:(1) to assess the effect on the quality of client-caregiver interaction by a treatment protocol designed around a specially developed mobile device. Moreover, attention will also be given to differentiation among…
The aim of this proposal is to investigate the potential use and value of experienced utility, as measured by the ESM and the DRM, in the economic evaluation of health care.Research question:1. What are the differences between the utilities measured…
Objective: Primarily, the objective of this study is to assess the role of serotonergic and dopaminergic polymorphisms in fear conditioning. Secondary, we will investigate additional cannabinergic and corticotropinergic polymorphisms in fear-…
To test the impact of the GABAergic system on fear responses by assessing the effect of genetically determined GABA concentrations in the amygdala on psychophysiological and neural correlates of fear learning and fear extinction.
What is the prevalence of depression and anxiety in children with asthma. Is this more frequent in asthma than in other chronic conditions like diabetes and Coelikie? And how compares this to healthy children in the same phase of life?
The present study will examine whether administration of a beta blocker (propranolol) and cortisol (hydrocortisone) to a healthy male population during retrieval of emotional memories in healthy subjects will lead to long term changes in these…
General objective of this project is to better understand the biological basis of PTSD patients. The study will focus on establishing multiple correlations of different PTSD subtypes with relevant psychological, biochemical, endocrinological,…
The main objective of the study is to determine whether, and if so, to what extent, there are differences in memory vividness, detail and certainty between OCD patients, another anxiety disorder patients and healthy subjects in a repetitive checking…
-Identify the neural correlates of enhanced formation of emotional memory, and parse the role of adrenal stress hormones in this process.-Identify the neural correlates of enhanced consolidation of emotional memory and parse the role of adrenal…
Testing the feasibility of testing FPS as part of an anxiety test battery several times on one test day (pilot study 1) and repeating this procedure across several test days (pilot study 2).
To explore the effect of stress on the neural correlates of emotion regulation, we will combine sophisticated behavioural tasks in a functional magnetic resonance imaging (fMRI) setting with a well-established stress-induction procedure.
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First, we want to examine whether a CBM training aimed at inducing positive appraisal style (positive CBM-app) can alter dysfunctional appraisal styles in PTSD patients. Second, we want to examine whether this CBM-app training has an effect on PTSD…
To further study effects of a single administration of cortisol, compared to placebo, on different aspects of attention and other cognitive processing of emotionally relevant information in healthy young men. This should provide new information on…