60 results
Investigating freezing patterns in response to aversive pictures in 2 specific clinical populations: patients with PTSD and patients with conversion disorder. This will provide new information about the role of freezing in the onset and maintenance…
1) To study the predicitve value of fear acquisition and extinction mechanisms on treatment outcome in anxiety disordered patients. 2) To study pathological fear acquisition and extinction in anxiety disorders: what are the differences in…
By achieving multiple measurements of ambulatory HRV and anxiety symptoms in one individual agoraphobia patient during a standard treatment at the University Center for Psychiatry (UCP), we will investigate how the bidirectional causal relations…
This project aims to investigate the role of sleep on memory processing in PTSD. The primary aim of the study is to assess the effects of sleep architecture on emotional memory processing and neurocognitive functioning in subjects with and without…
• To elucidate the role of noradrenaline in the mechanisms involved in human memory consolidation• Evaluate the levels of cortisol and 3-methoxy-4-hydroxyphenylglycol in the various points of a memory consolidation window• Define pharmacological…
The AMSTAD-OCD study aims to contribute to the improvement of outcome in OCD by identifying the determinants of a chronic course.
Part 1: Primary objective 1: Will OCD patients experience dissociative feelings during clinical perseveration?Part 2: Primary objective 2: Will OCD patients report more dissociative uncertainty after perseveratively repeating words than healthy…
Examining freezing in response to aversive stimuli in two specifieke clinical populations: borderline patients with and without comorbid PTSD. This will provide new insights in the role of freezing in the development and maintenance of these…
To assess differences in brain activation during the AA task in participants with SAD.
The primary objective is to investigate whether a brief (10+2 sessions) Cognitive Behavioural Therapy (CBT) program can (postpone or) prevent the onset of depression or anxiety disorder in an ultra high risk sample of 8-18 year old children of…
Goal of the study is to establish evidence on cognitive biases in a high risk population and on the longitudinal impact of such biases. We hypothesize that CPAD*s show biases in their information processing when compared to control children. We…
Study ObjectiveTo determine whether alprazolam, a registered anxiolytic non-selective benzodiazepine, can reduce the autonomic temperature increase induced with social stress in healthy men. Secondary objectives are to determine whether alprazolam…
The aim of this study is to examine if an increased number of awakenings in PTSD is PTSD dependent or trauma dependent. Furthermore, the purpose of the study is to examine if the nocturnal excretion of cortisol is increased.
Objective: To determine whether specific genetic variations, such as variable tandem lengths of repeats and polymorphisms, in certain genes are more prevalent in people with panic disorder than in controls. To determine whether contribution of these…
The aim of the present study is to establish intero-interoceptive fear conditioning in healthy participants in a differential conditioning paradigm. We want to make use of *real* interoceptive conditioned stimuli: a low respiratory load and small…
This study will investigate whether odors can be conditioned to fearful events and themselves elicit fear in humans. Fear conditioning will be tested on two odors: a pleasant odor and an unpleasant odor. The research questions are 1) can odors be…
This study intended to improve two different aspects in the treatment of PTSD-SUD patients. On one hand, one tries to optimize diagnosing PTSD by testing PTSD-screeners on sensitivity and specificity, with a diagnostic interview as golden standard.…
The current study assesses activation of hippocampus and prefrontal cortex during sleep spindles in veterans with and without PTSD. Furthermore, the correlation between sleep spindles and memory consolidation will be examined.
Major objectives:1. To measure basal salivary cortisol and DHEA(S) levels and salivary cortisol responses to low-dose dexamethasone in sexually assaulted adolescents with PTSD compared to cortisol and DHEA(S) values in non-traumatized controls. 2.…
To gain insight in the relation between maternal thyroid function and maternal emotional complaints during pregnancy and the development of the child in relation to the self-regulation capacities of the child.