18 results
Distinguishing frontal lobe epilepsy from ADHD in terms of working memory.
The aim of this research is, following the aforementioned theoretical framework, to investigate whether the two candidate genes in combination with EEG and fMRI markers differentiate between children that do and do not show a clinical response to…
Here we propose that in order to identify causal mechanisms that explain AD/HD-related heterogeneity, an integrative approach is needed. Therefore, in this project we will study the interaction between motivation and executive function in AD/HD and…
The primary objective of this study is to determine the prevalence of white matter lesions and subjective/objective neurocognitive functioning in women several years after pregnancy compared to nulliparous women The secondary objective is to…
Primary: to study the frequency and characteristics of fatigue and cognitive disorders after minor stroke. Secondary: to gain more insight in the aetiology of post-stroke fatigue and evaluate the impact of post-stroke fatigue on personal and social…
To determine the effects of surgical and transcatheter (transapical, transfemoral or transaortal) aortic valve replacement on patient neuropsychological functioning which provides the opportunity to prematurely establish subclinical effects that may…
The objective of the current experiment is to validate cognitive- and EEG-diagnostic markers of ADHD-symptoms by studying differences in cognitive task performance between subjects diagnosed ADHD, undiagnosed ADHD subjects showing ADHD symptoms and…
An online testing approach to assess cognitive problems associated with cancer and cancer treatment.
The aim of the proposed project is to develop a user-friendly and standardized online neuropsychological test battery. It will be a concise test, measuring those domains which have proven to be most sensitive to the adverse effects of chemo- and…
The primary objective of this study is to provide access to SPD503 following participation in SPD503-315 or SPD503-316. The primary outcome of this study is to evaluate the long-term safety of SPD503. The evaluation of safety will be based on the…
To demonstrate the extent to which an intervention that combines treadmill training augmented by virtual reality (TT+VR) reduces fall risk, improves mobility and enhances cognitive function in a diverse group of older adults, compared to a treadmill…
Objectives of the study: Project 1 - To assess early adaptive deficits in a multicentre cohort of mild to moderate TBI patients and their relation to outcome. Project 2 - Early intervention study of Cognitive Behavioural Therapy (CBT) to assess…
In this study, three main hypotheses are tested. The first hypothesis focuses on the expectation that an intervention aimed at training cognitive components of social competence affect the level of social competence and well-being of adolescents…
The principal objective of this study will be to critically evaluate if the fMRI-neurofeedback training is successful in reducing ADHD symptoms and improving cognitive functioning. Thus, the first goal is to show that ADHD patients are able to…
Primary objectives:This is a pilot study. The main objective is to investigate the feasibility of the study. This feasibility will be tested by estimating: 1. the percentage of inclusion, 2. the incidence of behavioural changes for which the GP is…
- To assess the safety and tolerability of escalating single and multiple IV doses of SAR228810 in AD patients- To evaluate the pharmacokinetic properties of SAR228810 in plasma and CSF after escalating single and multiple IV doses of SAR228810 in…
The main purpose of the proposed naturalistic pilot study is to compare postsynaptic DA receptor binding (reflecting synaptic DA concentrations) and brain Phe levels in PKU adults with lower blood Phe levels with PKU adults with higher blood Phe…
The primary goal of this project is to study whether children with ADHD differ from the normal population on the urinary and plasma levels of the AAA*s (tryptophan, tyrosine and phenylalanine) that are related to the functioning of serotonin and…
The objective of this study is to improve the understanding of subjective cognitive complaints expressed by patients with OSAS by:1. Comparing subjective cognitive complaints of patients with OSAS to healthy controls2. Studying the effect of…