77 results
To determine the effect of chronic use of ginkgo biloba on the single-dose pharma-cokinetics (AUC0-inf, AUC0-12, Cmax, C12) of raltegravir 400mg in healthy volunteers.
Investigate whether critical thinking of people with executive function deficits as a result of brain damage can improve by VTS.
The purpose of this trial is to research how the new medication SCH 900062 after single and multiple dosing is absorbed, broken-down and excreted by the body when in the fasting state and after eating a high fat meal. This trial is necessary for the…
Decreasing AB and subsequent craving through attention training in alcohol dependent patients. Further, we will investigate whether the risk for relapse diminishes after the training. Long term goal is to investigate the effect of attention training…
The objectives of this study are to establish whether methylphenidate PD effects can be measured using neurocognitive tasks, to describe the drug concentrations of methylphenidate in saliva, to describe the PK/PD relationship using the obtained…
Primary Objective: Using functional neuroimaging to assess differences in brain activation during WM at low and high load with emotional versus neutral distracters in participants with PTSD and in healthy participants with and without stress.…
The objective of the pilot study is to investigate whether a neurofeedbacktraining is a feasible intervention for youngsters with AD(H)D and severe behavioral problems. Besides the feasibility of the neurofeedbacktraining the clinical relevance of…
Primary:The primary objective of this study is to evaluate the efficacy of LDX administered as a daily morning dose (30, 50, and 70mg/day) compared to placebo over the course of 7 weeks. This study will enrol children and adolescents (6-17 years of…
To asses the clinical effect of low dose pipamperone on cognitive functions of elderly patients suffering from cognitive dysfunction.
Zie K1. NL
We aim to assess the effects of tyrosine supplementation on prefrontal brain activation, as measured by a combination of fNIRS and EEG, during response inhibition and working-memory performance in older adults. We will also assess whether…
To assess perioperative physical activity and fitness, and muscle strength in cardiac surgical patients and to explore the association with POCD after heart surgery.
Determining the long-term (18 months) effectiveness and cost-effectiveness of an elimination diet (ED) as the first addition to care as usual (CAU) in comparison to providing CAU only in children with ADHD (5-12 years). Hypotheses: Long-term…
Primary objective: To investigate the effectiveness of ongoing treatment with methylphenidate as prescribed in clinical practice beyond two years in children and adolescents. Secondary objectives:(1) to investigate the effects of discontinuation of…
The main aim of the TRACE-BIOME study is to characterize the role of biomarkers related to the microbiome-gut-brain pathways in the effect of an ED as a treatment for ADHD.
Primary objectiveTo assess whether the use of alimemazine improves symptoms of allergic diseases and ADHD, as scored by the parents using standardized questionnaires (Sample Snap IV rating scales)
The objective of this study is to study whether Eye Movement Desensitization and Reprocessing (EMDR) treatment leads to a significant decline of the negative self-image in patients with ADHD. The objective is to create a stronger improvement in self…
This study aims to investigate whether mijnfittebrein.nl has a positive effect on cognition in cancer patients after chemotherapy treatment, compared to treatment as usual.
The purpose of this study is to investigate how safe modafinil is and how well it is tolerated when it is administered in combination with aniracetam to generally healthy elderly volunteers with subjective cognitive decline. Modafinil and aniracetam…
To investigate the efficacy of targeted nutrient supplementation on daily physical activity level as well as generic health status in patients with moderate to very severe COPD. Additionally, we aim to disentangle the relative effect of targeted…