32 results
Objective of the project is to the American EDDI translate and adapt to the Dutch situation. Then, in a pilot study there will be examined whether the intervention is applicable to people with dementia and their caregiver, and if so, under what…
The main objective of this study is to determine the neural correlates of apathy. These neural correlates will be compared with the neuropsychological tests At a later stage, the predictive value of the neural correlates will also be assessed.
The present PhD thesis focuses on the investigation of ADAS and the older driver. Even though, recent research investigated the effects of ADAS on driving performance, little is known about the long-term effects of the systems on performance.…
The goal of this research project is to develop a multidisciplinary guideline for the responsible and restrictive treatment of freedom restriction in the care for elderly with dementia and people with intellectual disabilities. In this guideline the…
In the current study, the effect of oral health care and normal diet on quality of life of elderly persons suffering from dementia.The results from the baseline assessment will be used as cross-sectional data to establish correlations between the…
In the present project we aim to develop a first working platform for interactive, home-based blood pressure screening and monitoring by using internet and smartphone technology in middle-aged offspring of patients with dementia.
To study the short term effects of a pharmacological dose of fish oil on cognitive performance and on cerebral blood flow. Furthermore, we want to investigate whether carriers of the APOE*4 allele respond differently to fish oil treatment compared…
Primary Objective: Our primary objective is to test the feasibility of the online In-MINDD intervention through a primary care-based feasibility RCT. We hypothesize, that providing persons with information on their health profile and access to…
This project aims to determine the effects of an extensive exercise program in MCI patients with respect to the progression of the disease
The primary objective of this study is to assess the association between pre-dialysis comprehensive geriatric assessment and early death or withdrawal from dialysis (<6 months) in patients aged over 65 years
Main objectives are to investigate the cognitive effects of alternating endurance-strength training in APOEe4 carriers and non-carriers in early stage dementia and to identify a dose-response relationship of the cognitive effects of exercise.…
Our aim is to investigate the cognitive effects of an interactive cycling training in early stage dementia patients (in comparison to an aerobic cycling training and a control group).In addition we will investigate whether the effects of training…
The primary objectives are to study how exercise (i.e. actively performing exercise) affects frontal cortical activation (neurovascular coupling) and the effects on immediate cognitive performance of short periods of reduced and enhanced cerebral…
The primary objective is to determine if there is a difference in autonomic function between patients with Alzheimer*s disease (MCI and AD) and a matched control group. The secondary objectives will be explorative and aimed to investigate…
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To test the feasibility of supplying a tailored, digital health app, designed to increase insight in how to reduce one*s dementia risk, in the general practice. Secondly, we aim to explore the usability of experience-sampling method (ESM) technology…
The aim of this study is to evaluate the additional value of quantitative amyloid imaging analysis for modelling and assessing Alzheimer*s Disease (AD) dementia risk in individuals without dementia, compared to a range of existing cognitive, imaging…
The overall aim is to investigate whether a coach-supported mHealth intervention for lifestyle improvement can reduce the risk of dementia in those with low SES and/or a migration background aged 50-75 years. The specific objectives are to…
The purpose of this study is:To investigate how glutamate is processed in the brain using magnetic resonance, a non-invasive technique used to see images of your brain. Glutamate is a chemical that sends signals between nerve cells in the brain.