22 results
The primary objective of the proposed study is to examine the neural substrate of cognitive and social-emotional apathy in patients with schizophrenia. Secondary, we intend to explore the concentration of brain metabolites and structural differences…
1.Social CognitiveA.Do schizophrenia patients, compared to unaffected controls, show impaired social cognition (perceiving, understanding, intentions and emotions of others), especially when it comes to self-other distinction processes (…
The objective of the current study is to obtain normative data of healthy individuals on brain measures, cognition and blood markers. In addition, we acquire information on childhood trauma, metabolic and immunological parameters in a cohort of…
The aim of this project is to elucidate the mechanisms underlying one of the most incapacitating psychiatric disorders, psychosis. Despite antipsychotic treatment, up to a third of patients with psychotic illness continue to experience significant…
The first goal of this research is to translate the IMI-SR into a valid and reliable Dutch version of this questionnaire (N-IMI-SR). The second objective is to assess whether there is an association between IM and cognition in schizophrenia.
The aim of this study is to demonstrate the influence of a serious diagnosis like schizophrenia has happiness in relation to daily activities.
The aim of the current study is to investigate which gene-abnormalities can be related to brain deficits and symptoms associated with schizophrenia.
The aim of the proposed research is to test the hypothesis that lack of insight in psychosis is associated with reduced activation of brain circuits subserving self-evaluation and emotion regulation and that this relationship is also dependent on…
To investigate whether patients with schizophrenia show reliable and consistent brain activations as measured with fMRI to two different stimulation paradigms and wether they differ in terms of the patterns or the intensity of activation as compared…
Primary objective: the primary goal is to investigate the effect of audiobooks on quality of life, general psychopathology, the experienced power of the voices and the burden of the voices.Secondary objective: the second goal is to determine whether…
The objective of this study is threefold. First, to investigate neural correlates of cognitive-emotional processing in an ARMS sample, i.e. help-seeking young people with an at-risk mental state (this will be addressed in the base-line measurement…
This study looks if the third generation antipsychotic aripiprazole can improve activity of the prefrontal cortex and cognitive and social function, when compared to the second generation antipsychotic risperidone.
The aim of this study is to investigate the neural correlates of different types of emotion regulation and emotional processing underlying social cognition.
Beschrijven van het beloop van de kwaliteit van leven bij patiënten met kanker in samenhang met ziektecognities en copingstijl. Onderzoeken welke determinanten de ervaren kwaliteit van leven (mede) bepalen.
The aim of the proposed study is to investigate the presence of dopaminergic abnormalities in relation to apathy in persons with a high risk for psychosis. Second, we intend to explore the relation between the dopamine system and apathy in general,…
This research aims to generate knowledge about the sexual experience of clients with an SMI. Possibly the acquired knowledge can be used to create awareness among care providers. The ultimate wish is to adapt the treatment to the sexual experience…
The aim of the proposed study is to investigate the presence of dopaminergic abnormalities, as measured with [11C]raclopride, in relation to antipsychotic medication discontinuation in patients remitted after a first-episode psychosis (FEP).…
Primary objective:The primary objective is to answer the following research question:1. How do people who transitioned to psychosis describe alterations in their experiences of self and reality prior to the first psychotic episode? 2. Are these…
Discovering meaning and patterns in the relationship between experienced discrimination, cultural identity and psychosis in ethnicminorities by centering patients* experiences of in- and exclusion in a particular clinical context.Secondary…
This study aims to investigate if and how synaptic density may underlie cognitive deficits and whether functional connectivity is the intermediate step. In patients with psychotic disorders, cognitive function and brain connectivity may be decreased…