193 results
The primary aim of ICT4D is to design an intelligent monitoring and selfhelpsystem for use in Primary Care (Moodbuster). In this pilot study the feasibility and the usability if this intervention is tested among patients suffering from minor and…
To investigate the effects of a single dose of fludrocortisone, a mineralocorticoid receptor agonist, on emotional information processing in healthy female participants.
This randomized controlled trial examines whether a guided-self-help intervention is effective in treating depressive symptoms by employees. Cost effectiveness is also examined.
Primary objective:To show that concomitant use of telaprevir (1125 mg BID) does not lead to a relevant decrease (> 20%) in the paroxetine parameter AUC0-24h compared to paroxetine alone.Secondary objectives:To determine the ratio of the…
The aim of this study is to test in a single session study in participants with subclinical depressive symptoms, whether adding ABM to rTMS treatment might maximize the beneficial effects on attentional bias, attentional control and emotional…
The primary aim of this pilot study is to explore the feasibility and the usability of an innovative, combined internet and smartphone intervention for the prevention of depressive disorders among adults in the general population.
To investigate the effectiveness of Mindfulness Based Compassionate Living (MBCL) in recurrent depressive patients.
Primary: To evaluate the safety and tolerability following oral administration of multiple doses of BCI-838 in healthy male and female subjects Secundary:To determine the pharmacokinetic profile of multiple oral doses of BCI-838 in healthy male and…
The aim of this study is to examine whether MBCT is also effective in patients with chronic, treatment-resistant depression in a mental healthcare setting.
1) Are the effects of antidepressant treatment and exercise treatment on depression and/or anxiety symptomatology and general health indicators comparable? 2) Is recovery of depression and/or anxiety after treatment associated with reduced cellular…
We would like to test the system in a pilot study with vulonteers with mild depressive symptoms. The goals of this pilot are twofold:1) We want to know how easy to use the system is and how content the volunteers are with this form of treatment en…
Primary:- to assess the pharmacokinetics of the study drug and total radioactivity (TRA) and the routes and extent of excretion of drug-derived material after administration of a single 3 mg oral dose of 14C- labeled study drug in healthy male…
Primary:to explore the routes and rates of elimination of [14C]-radio labeled RO5200628 after oral administrationto determine the pharmacokinetics of total drug related material, RO5200628and its metabolites as appropriateSecundary:to investigate…
The primary research question is:1. Is there a difference in the usage of memory strategies between both groups?The secundary research questions are:2. Is there a difference between both groups in the types of memory strategies they use or don*t use…
Investigate the effect of the Etomidatelevel on the seizure-quality of a seizure caused bij electroconvulsive therapy
Does ECT in combination with nortriptyline result in a more likely and or faster response than ECT alone? Does continuation pharmacotherapy with nortriptyline result in a lower relapse rate or longer time to relapse in responders to ECT in…
The objective is to assess the effectiveness of exercise therapy (running therapy or Nordic walking) on depression in adults, in addition to usual care (primary aim) and on metabolic syndrome measures, quality of life and cost effectiveness (…
The aim of the present study is to evaluate the efficacy of a protocol for cognitive behavioral treatment (CBT) of psychological distress as a component of multidisciplinary treatment in SSc on psychological distress.
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The project aims to establish whether CBASP can be a good addition to the current range of treatments for chronic depressive patients in second-line mental healthcare services. This group of patients is amply represented within institutions for…