58 results
In patients over 60 years of age who have sustained a displaced femoral neck fracture, what is the rate of revision surgery at 24 months when a total hip arthroplasty versus hemi-arthroplasty is used as the surgical treatment? Hypothesis: We…
The objective of this study is to develop a resistance training intervention that improves mobility and quality of life in diabetic patients. It is also our intension to achieve a better understanding of the relation between diabetic neuropathy and…
To determine if denosumab is non-inferior to zoledronic acid (Zometa) with respect to the first on-study occurrence of a skeletal-related event (SRE) in men with hormone-refractory prostate cancer and bone metastases.
The objectives of this study are:* To determine the percentage of patients with recent-onset RA and UA who achieve and maintain clinical remission on treatment with a combination of methotrexate 25 mg/week and extended prednisone pulse (tapered high…
This is the first study of MLN3897 in any disease population. It seeks to establish:1) The ability of MLN3897 to modify the signs and symptoms of RA.2)The safety and tolerability of MLN3897 in combination with MTX.3)The PK/PD profile of MLN3897 in…
The aim of the present study is two-fold: 1) To do a survey of patients who have been prescribed a SC-KAFO in the outpatient clinic and evaluate the indication of prescription, compliance, experience and motives for (non) use of the SC-KAFO. 2) To…
The study aims to examine whether the emotions anger and sadness influence pain and fatigue in female patients with fibromyalgia and a control group from the general population and whether physiological reactivity and individual differences in…
To clearify the etiology of CTS and prognostic factors for the development of CTS.
Aim of the study is to describe and evaluate an alternative physical therapy management program in patients with a complex regional pain syndrome type 1. A secondary aim is to describe the adverse effects that occur during or after the intervention.
Objectives. The goals of the current protocol is therefore the natural follow-up of the objectives achieved with the previous grants and, in particular, of projects designed to discern new models for the successful conduct of clinical trials in…
Primary Objective: The primary objective of the study is to assess long-term safety of AMG 108 (125 mg, 250 mg) SC in subjects with RA previously enrolled in study 20050168.Secondary Objective(s): The secondary objectives of the study are:* To…
In this study, we study whether there is a difference between the utilities that patients with Rheumatoid Arthritis assign to their own health and those that they assign to the EQ-5D scenario describing that health (lack of scope). Further, we aim…
The first objective is to evaluate the safety of cetuximab in patients with scleroderma associated PAH. The secondary objective is to assess efficacy.
To determine if denosumab is non-inferior to zoledronic acid (Zometa) with respect to the first on-study occurrence of a skeletal-related event (SRE) in subjects with advanced breast cancer and bone metastases.
Primary objective is to demonstrate that the effectiveness of thesurgical intervention with X STOPPK is equivalent to surgical decompression without fusion after 1 year after surgery.Secundary objectives are to demonstrate that surgical intervention…
The purpose of this study is to investigate the effectiveness of a website.If the results indicate that the website is effective, the website may be implemented on a large scale. With the use of an effective website, companies will receive better…
The objective of this pilot study is to investigate the feasibility and effect of a high-intensity physical training program for elderly patients who are scheduled for abdominal oncological surgery on the preoperative maximal aerobic capacity and…
The primary objective of this study is to investigate whether application of PRF® will reduce postoperative wound leakage, the necessity for allogeneic blood transfusions and the incidence of wound healing disturbances in patients undergoing…
To determine if denosumab is non-inferior to zoledronic acid with respect to the first on-study occurrence of a skeletal related event (SRE) in subjects with advanced cancers and bone metastases (or lytic bone lesions from multiple myeloma).SRE is…
The aim of this project is to do an objective and subjective functional long-term outcome assessment of patients with distal radius malunions, treated with intraarticular osteotomy and therefore evaluate factors that are good outcome predictors for…