162 results
to determine the percentage of patients with CKD, without a history of gout or attacks of arthritis, that have tophi measured by US,DECT and clinical examination. to determine the percentage of patients with CKD, that have tophi measured by US, and…
Primary aim: Stepwise feasibility study to investigate whether intravenously administered macrophage tracers [11C]DPA-713, [18F]DPA-714 and/or [18F]PEG-folate accumulate in inflamed joints of rheumatoid arthritis patients using PET(-CT).Secondary…
Feasibility of knee motion reproduction method for application in a hinged knee distraction device to apply reliable comfortable hinged knee joint distraction to be tested in future clinical studies.
The main objective is to identify objective, neuromuscular and/or mechanic parameters through movement analysis, which are closely correlated to the subjective outcome of TKA. Secondary objective is to generate parameter specific hypotheses for our…
The main objective of this study is to assess the prevalence cardiovascular disease and the prevalence of risk factors for cardiovascular disease in patients with gout, and to quantify the risk for cardiovascular disease in patients with gout. The…
The aim of this exploratory study is to compare the hemodynamic response as determined by the HandScan between patients with OA and RA, and to study these hemodynamic responses in relation to disease specific underlying joint pathology (synovial…
To evaluate the role of white blood cell (WBC) scintigraphy in monitoring the response of infection treatment of a prosthetic joint infection.
The aim of the basic research in the laboratory is to develop new treatments to repair large bone defects, repair cartilage defects or inhibit the progression of osteoarthritis (cartilage degeneration). We focus on the following questions:1.How can…
To assess the clinical and cost effectiveness of the anterior approach, compared to the conventional posterolateral approach for THA in terms of physical functioning and health-related quality of life
Till date no (other) large long-term follow-up study of children with ACL ruptures has been published with a follow-up period of minimally 10 years. Therefor, the long-term consequences of ACL ruptures in children are still unknown, especially with…
Define the normal outcome and spread of the range of motion of the knee-rotationThe outcome of the manual rotationtest of the knee compared with a rotation-device. (reliability of the test)Define inter- and intra-tester reliability of the manual…
The purpose of this study is to investigate the relation between scapular movement, muscle activation and cranial translation in healthy volunteers.
Primary Objective: (diagnostic)• Does MRI detect structural changes of haemophilic arthropathy in knees and ankles undetected by the Pettersson score and HJHS? (Research question 1 a & b)Secondary Objective(s): (prognostic)• Can MRI predict…
To evaluate the prevalence of femoral head pathology in patients with MPS III.
Arthroscopic Optical Coherence Tomography in imaging of Trapeziometacarpal joint articular cartilage
In-vivo visualization of TMC articular cartilage using intra-articular fiber-optic OCT during TMC arthroscopy.
Primary Objective: Compare grip strength of working patients with OAH with healthy workers.Secondary Objective(s): To compare the results of the supplementary tests of working patients with OAH with healthy workers.To describe the possible…
To estimate the prevalence and burden of disease of PsA among PsO patients in primary care,.To test the ability of the PEST(1), the PASE(2) and the EARP(3) to detect cases with PsA in primary care.To develop an easy applicable prediction rule for…
Primary objective:Pharmacokinetics/-dynamics of 124I-F8IL10 Secondary objective:Dosimetric parameters of arthritic joints and internal organs.
To evaluate the clinical impact of the CaFaSpA referral rule in young patients presenting at the general practioners with chronic low back pain, who are at risk for axSpA, compared to usual care.
In the present study we evaluate the change in quality of cartilage and bone as a result of KJD and of HTO. Based on the results of this pilot study, we will design a clinical study, with sufficient power, using the most promising sequences to…