21 results
Primary Objective: To assess the safety of the single flap peritoneum vaginoplasty procedure by studying adverse events and complications during, directly after and within 90 days of the operation. Secondary Objectives: - To assess short- (12 weeks…
Objective: Evaluate uterine contraction features (frequency, amplitude, direction, and coordination) using a dedicated speckle-tracking algorithm by 2D transvaginal ultrasound measurement in postmenopausal women presenting with vaginal bleeding or…
Primary Objectives: 1) Is it feasible to implement plane-wave imaging in a combined DBT-US device to decrease scan time while preserving or improving image quality compared to conventional imaging? 2) How do DBT images compare obtained by DBT with a…
The objective of the MENDiP-study is to determine the feasibility to detect the absence of nocturnal erections with overnight penile temperature sensors. By including patients undergoing a radical prostatectomy, absence of erectile functioning is…
The objective of the Feeling Hot 1 study is to determine the change in penile skin temperature regarding the temperature increase and sensor response time during visually aroused erections when considering environmental influences of overnight…
1. To study the possibility to detect gynaecological malignancies and endometriosis in Pap smears and blood of women with gynaecological cancer or endometriosis, using MeD-seq and biomarker assays, in order to develop new reliable screening methods…
Objective: This protocol describes a framework that will be used to create different studies. The general primary and secondary objectives of this protocol are stated below:Primary objective: Investigate the effect of surgery on the position and…
This study aims to validate the potential of immune related biomarkers to predict the clinical response of patients with primary cHSIL to imiquimod and aims to explore the value of these immune biomarkers in recurrent/residual cHSIL to predict…
This study has been transitioned to CTIS with ID 2023-505455-44-00 check the CTIS register for the current data. Part 1 (phase 1b)Primary:• To observe the safety and tolerability of bemarituzumabSecondary:• To evaluate preliminary antitumor activity…
Evaluate the clinical progression free survival after randomization to either 6 months of androgen deprivation therapy (ADT) or 6 months of ADT plus a 99mTechnetium (99mTc)-based PSMA-radioguided salvage surgery.
In the present study the clinical feasibility and safety of MR-guided focal boost radiotherapy for patients with locally advanced prostate cancer will be evaluated.
The primary objective is to gain more insight in molecular alterations in CSU by performing a broad set of molecular analysis on tissue and blood ofpatients with carcinosarcoma of the uterus and find (bio)markers which can be linked to the clinical…
To investigate if surgery is feasible and safe in patients with newly diagnosed lymph node metastatic HSPCa who have received two cycles of (neo-adjuvant) systemic 177Lutetium (Lu)-labeled prostate-specific membrane antigen (PSMA) radioligand…
The project aims are to 1) provide an integrative understanding and conceptualization of uncertainty in transgender and DSD/intersex care, and to 2) support children/adolescents, parents and healthcare professionals in recognizing, discussing and…
Primary Objectives: Determine oncologic outcomes after fertility-sparing treatment in AYAs with cervical, ovarian or endometrial cancer (Q1). Determine fertility and obstetric outcomes after fertility-sparing treatment in AYAs with cervical, ovarian…
To evaluate the efficacy of triptorelin embonate 22.5 mg 6-month formulation administered subcutaneously in maintaining serum testosterone castrate levels in participants with advanced prostate cancer previously treated and castrated with a GnRH…
We aim to investigate how chromosomal mosaicism affects development of the different embryonic and extra-embryonic tissues of the peri-implantation blastocyst and early post-implantation embryo to understand why some mosaic embryos can continue…
This study has been transitioned to CTIS with ID 2024-517646-34-00 check the CTIS register for the current data. The objective of this study is to evaluate the effect of enzalutamide on morphine and edoxaban pharmacokinetics. This information is…
The objective of the Feeling Hot 2 study is to determine the change in penile skin temperature during nocturnal erections, which will be detected by the RigiScan. Furthermore, the effect of nocturnal erections on the outer thigh skin temperature is…
The primary objective is to investigate the effect of an anti-inflammatory diet on HRQoL and pain symptoms in women with endometriosis. The secondary objective is to investigate the effect of an anti-inflammatory diet on inflammatory characteristics…