45 results
The aim of the current study is to identify couplings of muscle activation patterns (muscle synergies) in reaching movements in stroke patients. Insight in the motor control of stroke patients can contribute to improve the disabled arm functioning…
The primary objective of this study is to determine the prevalence of white matter lesions and subjective/objective neurocognitive functioning in women several years after pregnancy compared to nulliparous women The secondary objective is to…
Objective: Development of an instrument to objectively assess arm-hand skilled performance in daily life in typically developing children, children with CP and adults who suffered a stroke.
The primary objective is to test the feasibility of MRI measurements at 3T and 7T under dynamic hypercapnic or hyperoxic conditions controlled by digitally regulated respiratory challenges in volunteers.
1) elucidate the role of the postural CO decrease on cerebral hemodynamics, 2) test the influence of posture, ageing and T2DM on the CO-VO2 relationship. Furthermore, 3) we want to determine the shape of the CO-VO2 relationship.
Overall objective:The overall objective is to test the hypothesis that GLP-1 receptor activation of CNS reward and satiety circuits occurs, in the context of food(-related) stimuli, and that this effect is altered in individuals with obesity and…
This study should show whether patients with focal BG lesions are impaired in changing the threshold between deliberate fast or accurate conditions, and between conditions with and without prior information. Also, it should show that patients with a…
The purpose of this study is aimed at the effects of early discharge from a hospital followed by adequate rehabilitation planning in a nursing home. It concerns a (cost)effective evaluation of a renewed stroke care model that was implemented in 2006…
(1) Evaluate whether stroke patients differ from healthy controls on the experience and the course of subjective cognitive complaints during the first two years after stroke;(2) Evaluate potential predictors for cognitive complaints during the first…
The main objective of this study is to examine the effect of different kinds of augmented feedback on learning an arm motor task.
1. To investigate whether a single-blind, randomized controlled trial in patients with a TIA or minor stroke addressing secondary prevention, healthy life style and cognition is feasible and not too demanding for the patient.2. To investigate…
The purpose of this project is to determine the impact of pretreatment fibrinogen gamma*/ total fibrinogen ratios on the success of rtPA therapy.
Primary objective: To provide a detailed description of the prevalence and cognitive characteristics of navigation impairment in stroke patientsSecondary objectives: To increase knowledge about the neuroanatomical correlates of navigation ability…
The objective of this study is to investigate whether impaired balance control is (partly) responsible for the increased energy cost of walking in stroke patients and amputees by evaluating the effect of external stabilization and destabilization on…
The main objective is to assess the added diagnostic value of biomarker assessment beyond the clinical assessment in patients suspected of TIA in primary care. Secondary objectives are i) to assess the prognostic value of biomarker assessment in…
To study HPA axis regulation and sympathetic nervous system activity in survivors of childhood ALL during relaxation and during stress.
The objective of this study is to determine whether the dichotomization in good and poor outcome by the composite scale, corresponds better with the parents' and doctor's opinion on the outcome than the PSOM. The composite scale willl be…
The objectives of this experiment are twofold. First, the muscle activation pattern related to a synergistic movement during reach is investigated, with attention for the existence of a threshold of amount of exertion above which an abnormal synergy…
The basic question of this project is to what extent the (long term) functional behavior of critical paretic lower leg muscles during standing and walking can be understood and predicted by (early) assessment of the integrity of the corticospinal…
The main objective of the study is: what are normal values for TMS parameters of arm extensor muscles in healthy human subjects? Secondary objectives are: (1) which forearm extensor muscle is most appropriate for a TMS study and (2) what is the…