453 results
1. To demonstrate the clinical efficacy of leuco-methylthioninium bis(hydromethanesulfonate) (also known as LMTM,TRx0237) in mild Alzheimer*s disease as assessed by change from baseline on:• Alzheimer*s Disease Assessment Scale - Cognitive Subscale…
In this study the effectiveness of online cognitive flexibility training on cognitive functioning in stroke patients will be investigated. The aim of this study is to improve executive functions: both trained executive functions as well as untrained…
Primary Objective:- To evaluate the efficacy of PF-04360365 (ponezumab) in subjects with probableCAA as compared to placebo on a BOLD fMRI measure of cerebrovascularreactivity.Secondary Objectives:- To evaluate the efficacy of PF-04360365 (ponezumab…
To determine the effect of botulinum toxin type A injections in stroke patients with stiff knee gait.
To further investigate the pathogenesis of DCI and its relation to gender, decreased fibrinolysis, increased coagulation, and hormonal factors in order to eventually pave the way for new treatment options.
To determine the incidence of hypopituitarism in patients after SAHTo identify neurological parameters that predict hypopituitarism after SAHTo determine the value of a Ghrelin test shortly after SAH, to identify subjects with GHD.To determine the…
1. To determine the diagnostic accuracy, in terms of detecting a vascular malformation, of CTA, MRI/MRA, DSA, or combinations thereof in patients with ICH?2. To find out which test or combination of tests is most effective for the detection of…
This study aims to determine the following: * What is the nature and extent of relational and sexual problems of stroke patients and their partners. * What is the time course of the relational and sexual problems of stroke patients and their…
1) to investigate cognitive functioning in lacunar infarct patients with and without periventricular white matter lesions; 2) to identify predictors for cognitive dysfunction in lacunar infarct patients.
Primary objective: to assess cortical activity post stroke in a repetitive way to determine cortical involvement in dedicated motor tasks and to relate cortical activity to clinical outcome prospectively after stroke. Secondary objective: to assess…
To compare the feasibility and safety of surface cooling to 34, 34.5, and 35*C, started within 4.5 hours after the onset of acute ischaemic stroke and maintained for 24 hours, in awake patients on a stroke unit.
To explore the underlying mechanisms explaining walking ability and walking activity.
The proposed study aims to test the acute effects of tDCS on chronic hemispatial neglect. In this particular application of tDCS the damaged hemisphere will be activated and the healthy hemisphere inhibited.
The primary objective is to investigate which balance and reaching performance measures - estimated using body-mounted sensing - correlate with frequently used clinical assessments of balance and motor function, while measuring stroke patients in a…
Assessment of the diagnostic accuracy of CTA for the detection of vasospasm after SAH in comparison to TCD.
The main objective of the proposed study is to examine the relative efficacy of C-Mill gait adaptability treadmill training compared to the Nijmegen Falls Prevention Program (NFP program) for improving walking ability aspects, particularly walking…
To investigate the risk of deeath and incident (cardio)vascular disease in patients with a TIA or stroke aged 18-50 yearsTo investigate the riks of cognitive impairment and (vascular) dementia in patients with a TIA or stroke aged 18-50 yearsTo…
Investigating the effectiveness of tCS on the recovery of neglect in sub-acute ischemic stroke patients suffering from neglect to complement conventional treatment
The primary objective of this study is to examine user acceptance and assess changes in arm function by people with chronic stroke following technology-supported arm/hand training at home. Secondary objectives are to examine whether stroke patients…
Objective: Development of an instrument to objectively assess arm-hand skilled performance in daily life in typically developing children, children with CP and adults who suffered a stroke.