34 results
To study sensory processing and hyperexcitability in children with ASD and epilepsy using neurophysiological measurements (EEG/ERP).
To establish the incidence and consequences (impairments op body functions, limitations in participation) of traumatic brain injury in children and youth in a region of The Netherlands as well as the incidence of the same symptoms in a group of…
Primary objective of the study:To find out which areas in the brain play a part in the maintenance of tinnitus, and what the roles of those areas are. This will be done using the AEP response in EEG recordings.Secundary objectives of the study:1. To…
The purpose of this research project is to assess whether affected PKD patients have brain abnormalities compared to healthy normal controls. Hypothesis: Paroxysmal kinesigenic dyskinesia affected individuals exhibit abnormal spontaneous activity of…
Main objective is to study changes in in vivo blood viscosity during mild therapeutic hypothermia and rewarming in patients after cardiac arrest. Secondary objectives are to study the effects of cooling and rewarming on-Hemodynamic parameters-…
In a randomized controlled trial, the effects of DHCA and ACP during complex neonatal cardiac surgery on organ function and injury will be compared, especially focusing on cerebral damage and neurological outcome. The primary research question is…
To set up a repository of genetic material from a large group of well phenotyped people with epilepsy patients to allow the case control association studies, and families for linkage studies, to analyze and detect genetic risk factors for epilepsy.
The aim of the study is to identify genes that cause early onset Alzheimer dementia, dementia with Lewy bodies and frontotemporal dementia.
Primary: To find out which areas in the brain play a part in the maintenance of tinnitus, and what the roles of those areas are. This will be done using BOLD response fMRI imaging.Secondary: 1. To find out which areas in the brain play a part in the…
The present study intends to perform functional magnetic resonance imaging (fMRI) in order to obtain further insight in effects of selective attention on sensory processing. This study aims to compare subjects with normal hearing to patients that…
The current study employs functional magnetic resonance imaging (fMRI) to investigate the auditory and limbic areas in tinnitus patients by means of innovative analysis methods that permit the assessment of functional interactions between brain…
Our overall aim is to obtain a better understanding of brain network damage in dementia patients. We propose a research project with two key objectives:1. Develop improved methods to describe functional brain network damage2. Relate network damage…
Primary:1. Which outcome variables of oculomotor performance and eye-hand coordinatio are useful to distinguish between Dementia with Lewy bodies, Alzheimerdementia and Parkinsondementia.Secundary:1. What are the base line values for the parameters…
The objective of this study is to proof the presence of lesions in the brain of patients with overactive bladder and urge-incontinence (OAB wet) as a central cause of this disorder. This survey is a pilot investigation for a larger study on the…
1) To compare fTCD with fMRI, in order to reproduce the previously shown high correlate between the two techniques. 2) to compare rTMS with fMRI and subsequently with fTCD.
Primary objective: the primary objective of the present study is to assess whether apathy can be linked to structural brain changes (both atrophy of grey matter, as well as changes in white matter), whether apathy in PD is related to certain…
To perform a genetic study of left-handedness and language lateralization as endophenotypes of schizophrenia. The study will make use of 30 extended multigenerational pedigrees with multiple left-handers from Urk, an isolated population in The…
We aim to investigate, for the first time, differences in frontal activation between healthy elderly people from Okinawa and the Netherlands. We predict that the Western European elderly will show an "MCI-light" pattern, whereas the…
The main objective is to determine the change in CS parameters upon administration of tapentadol in comparison to pregabalin in patients suffering from chronic pain that has a visceral or deep somatic origin.
Our objective is to find predictive biomarkers for disease progression in RVCL-S, a monogenetic small vessel disease, and to dissect disease mechanism to identify new treatment targets to improve health for RVCL-S patients, which may also serve as…