39 results
Primary:The primary objectives of the study are to estimate and rank-order the longitudinal standardized mean changes over 6 months and over 12 months, for a set of novel outcome measures administered to subjects with ALS, in order to identify…
To evaluate whether neuromuscular ultrasound discriminates between patients with and without ICU-AW.To detect differences between patients that do and do not have ICU-AW in order to determine relevant cut-offs which can be used in future diagnostic…
The primary objectives of this study are (a) to evaluate reliability and precision of an instrumented spasticity assessment device (ISA) in children with cerebral palsy and adults with spastic paresis (MS and stroke patients) and (b) to validate ISA…
Main objective: - Obtain long-term clinical follow-up data in PLS patients to investigate the reliability of the diagnosis PLS. - Obtain data on cognitive functioning to investigate the possible relation between PLS and FTD.Secondary objectives: -…
To obtain normal values for neuromuscular ultrasound parameters in adults.
In this pilot study we aim to investigate the additional value of sEMG signals of respiratory muscles during ICU admission in adults.
To optimize ventilator support in critically ill patients admitted to the intensive care unit by monitoring electromyography of the respiratory muscles.
To develop a screening test to predict ICU-AW at an early stage in patients admitted to the ICU. Also by prospectively following the patient group in time, this study aims to describe the natural history and functional limitations in patients…
The purpose of this study is: 1) to develop a method to quantify muscular fat content in brachial plexus injury patients;2) to investigate whether muscular fat content is more in the affected arm compared to the contralateral arm in BPI patients;3)…
Main objectiveTo describe the experienced pain sensations of temperature and to describe the different temperature sensitivity thresholds using Quantitative Sensory Test (QST) in the different patient groups.secondairy objectiveAs a measure of the…
In this research project, we will investigate the feasibility of multi-unit microneurography for the research of human muscle mechanoreceptors. We will therefore answer the following questions:1) How hard is it to find and maintain an effective…
The objective is to describe the nature and underlying (neuromuscular en biomechanical) factors of dysphagia in different neuromuscular diseases in relation to different consistencies of food. Identifying the contributing factors are starting points…
The main objective of this study is to compare DTI findings of PPS patients with those of healthy controls. Secondary objective of this study is to correlate DTI findings with clinical data such as isometric muscle strength. Third objective is to…
The purpose of this study concerns at a standardized way identifying the phenotype of patients with mt.3243A>G mutation, and relatives in the maternal line of patients with the mt.3243A>G mutation
Using state-of-the-art MR methods, this project aims to acquire a detailed understanding of the biochemical, structural and genetic background of the cognitive impairment in DMD and to determine whether the previously found differences between…
This study will consist of two parts. In the primary observational part we will assess kinematic and kinetic walking patterns in Duchenne Muscular Dystrophy. Goal is to asses the correlation between progressive contractures and gait patterns. This…
The goal of this research is to determine whether multi-unit microneurography can be a practically useful technique for recording human muscle-afferent signals, and to determine which fiber types are present in the recorded signal to and from the…
Our goal is to acquire a practical, maybe even clinically useful microneurographic technique. In this research project, we will investigate the usefulness of multi-unit microneurography for the research of human muscle mechanoreceptors, by answering…
The aim of this study is to describe the values of the SNIP in patients with neuromuscular disease and various respiratory conditions and to assess the practicability of the SNIP in these patients.
Which position of the person and which positions of the electrodes on the shoulder create the best recorded and best reproducible muscle amplitude?