14 results
The present protocol addresses these issues, with a systematic approach where we first assess optimal settings for BCI, and then test the quality of BCI application in adequately sized groups of subjects. The whole project is aimed at obtaining a…
The primary objective of this trial will be to evaluate the effect of ONO-2506PO (1200 mg once daily) on the slope of respiratory function (slow vital capacity (SVC) expressed as a percentage of the predicted value) over 12 months compared with…
There are some unresolved issues that we intend to address in this project. We will examine 1) whether with locating the motorcortex with functional MRI, the best location of the electrodes can be predetermined, 2) how brain activity changes in the…
The goal of this research is to determine whether multi-unit microneurography can be a practically useful technique for recording human muscle-afferent signals, and to determine which fiber types are present in the recorded signal to and from the…
The aim of this study is to investigate whether the new joints for the sc-kevo's can be effectively operated by the patient, and whether a minimal hip extensor strength is needed to operate the joints succesfully. Secondly, the effect of the…
Main objective Because this study will include young children (0-3 years old) the challenge is to measure isometric muscle force adjusted to their natural behavior. From 4 months old a child can pull a toy towards himself. Therefore we want to use…
The objective of this extension study is to assess the long-term safety and efficacy of Myozyme treatment in patients with Late-Onset Pompe Disease who were previously treated under the placebo-controlled, double-blind study AGLU02704.
Our goal is to acquire a practical, maybe even clinically useful microneurographic technique. In this research project, we will investigate the usefulness of multi-unit microneurography for the research of human muscle mechanoreceptors, by answering…
The aim of this study is to describe the values of the SNIP in patients with neuromuscular disease and various respiratory conditions and to assess the practicability of the SNIP in these patients.
Is it possible to stimulate a eye muscle or underarmmuscle for a prolonged time in a painless way and is this information contributory to make the diagnosis and grade clinical in MG and LEMS?
Which position of the person and which positions of the electrodes on the shoulder create the best recorded and best reproducible muscle amplitude?
The goal of this research is to discover if there is an improvement in the walking ability when someone walks with the Foot-up compared to the plastic AFO and walking without an AFO. The Timed up-and-go test will be used to look for this improvement…
This study aims to determine choices for stimulus number, frequency and duration that cause minimal discomfort to subjects. In addition, it will assess reproducibility and the effect of going up or down in stimulus intensity for the APB.
Using a nighttime sleep recorder, we want to answer the following questions:1. description of sleep quality (duration, efficiency and structure of various stages of sleep)2. quantification of specific sleep disturbances (RLS, OSAS and periodic limb…