132 results
To improve the behavioural (neuropsychological) methods for the early diagnosis of Alzheimer*s disease (AD) and other dementias.
This project has been defined to investigate the effect of therapeutic horse riding on balance, spasticity and general wellbeing in 30 adults in the age of 18-80 with physical impairments following a stroke or non-congenital brain injury.
Our general objective is to find out whether impaired communication within networks of specific brain regions underlies the cognitive control- and social problems of individuals with NF1. It is very important to examine these relations in children…
The current study further investigates residual vision in hemianopics by using a new measure of distractor interference on saccadic eye movements. Previous research with healthy participants has indicated that irrelevant distractors evoke saccade…
The eventual aim of the study is to determine the effects of Botulinum toxin injections in the bladder on overactive bladder. The objective of this initial study is to determine what brainstructures are activated in respond to increasing volumes of…
The primary objective of this study is to objectivate neural hyperactivity at the cortical level of chronic tinnitus sufferers compared to control subjects with the use of FDG-PET-scans.
Primary Objective: In this study, we will investigate the feasibility of a newly developed methodology for diagnosing the visuoperceptual hemifield abilities of young children with early damage to the visual system. Secondary Objective(s): Secondary…
Protocol 1: To determine whether pituitary dysfunction is present at intermediate duration of follow-up after traumatic brain injuryProtocol 2: To determine whether injury to brain tissue that explains traumatic brain injury-induced pituitary…
High-field (7T) MRI and genetic biomarkers for neurocognitive impairment in type 2 diabetes melltius
The primary objectives: 1. To tailor and apply high-field multi-parametric and functional MRI techniques to identify cerebral biomarkers in DM2 and MetS patients compared to control subjects.2. To examine a specific set of genetic hypotheses in DM2…
To study the acute effect of HD on global and regional CBF.
Our objective is to obtain insight into whether and how the visual and auditory systems of hemispherectomized patients have adapted after brain damage and brain surgery in early life. For this purpose we will perform psychophysical tests and (…
Primary Objective: • To demonstrate that changes in blood pressure and cerebral perfusion (induced with paced breathing and the Cold-pressor test) can be assessed in the MRI using the combination of NIBP and rapid ASL measurements. Secondary…
To assess how measures of microvascular function on 7T MRI in individuals from the Rotterdam Study without a history of clinical stroke or dementia relate to:- Exposure to vascular risk factors - Severity of presymptomatic SVD lesions- Cognitive…
The general objective of this study is to gain more understanding of motor and cognitive impairment and the way these two are linked after stroke. There are two more specific objectives: exploring (1) the link between motor and cognitive impairment…
The main objectives are to understand how clinical markers and biomarkers previously identified in younger and older AD cohorts apply to the extreme elderly (90+ years old) and to identify novel biomarkers linked with resilience to developing…
Primary Objective: To test the feasibility of online neuropsychological assessments using the Amsterdam Cognition Scan (ACS) compared to classical neuropsychological assessments in patients with cancers with CNS involvement.
To investigate the effect of explantation of silicone breast implants on neuroimaging of the brain (fMRI) in ASIA syndrome patients to gain more insight in the neurophysiological basis and nociceptive system of ASIA syndrome due to SIIS and the…
Primary objective of this study: To establish glycocalyx properties of temporal lobe epilepsy (TLE) patients. Secondary objectives of this study:- To establish differences in glycocalyx properties of glycocalyx between TLE patients and controls.- To…
Primary ObjectiveOur primary objective is to investigate the effect of SVD-progression on the long-term clinical outcome. Secondary Objectives- To identify causes and risk factors related to an unfavourable clinical outcome over time- To identify…
This study has been transitioned to CTIS with ID 2024-517636-22-00 check the CTIS register for the current data. The main objective of the present study is to investigate the association between in vivo regional synaptic loss ([18F]SynVesT-1 PET),…