627 results
to investigate the analgesic effect of high frequency 10 Hz rTMS on experimental pain measured through quantitative sensory testing (QST) in healthy subjects.
To assess the association between baseline blood pressure and change in neurocognitive functioning after four years, and to assess whether baseline MRI phenotypes are predictive for changes in neurocognitive functioning after four years in the DANTE…
The aim of the study is to expand an existing infrastructure for scientific research, i.e. a longitudinal observational study, for investigating physical, emotional, cognitive and social trajectories of functioning, their determinants and their…
Objectives: 1. To assess the prevalence of pain in elderly with dementia and to study the relationship between the various subtypes of dementia and the presence of specific types of pain(e.g. nociceptive pain, neuropathic pain, and orofacial pain).…
This study aims at, first, assessing the most relevant exposure aspects of night-shift work and, second, identifying biomarkers for both acute and chronic circadian disruption associated to these specific nightshift work aspects. By applying…
The primary objective of the study is to determine whether patients with PA have a higher level of arterial wall inflammation than patients with essential hypertension. Secondary Objectives: To determine whether circulating monocytes of patients…
The objective of the study is to determine the protein profile of cerebrospinal fluid of non-pregnant women using mass-spectrometry.This study is a follow-up project on the previously performed study (LEPRA, CSF and pre-eclampsia, MEC 2007-087). In…
To map phenomenolocal characteristics of hallucinations and delusions in psychiatric and neurologic patient populations as well as in the general population. By comparing this between all groups, different subtypes of hallucinations and delusions…
The goal of this study (mono-center study) is to study the effect of renal denervation with the EnligHTN Renal Denervation System on sympathetic nerve activity.
1. the primary objective of this study is to examen the incidence and prevalence of PTSDand depression in pre-eclampsia patients after delivery2. a secondary objective is to identify risk factors during pregnancy, durante partu and postpartum…
Primary Objective: To objectively and subjectively investigate sleep and fatigue among Dutch and British offshore workers and their influence on health safety and performance.Secondary Objective(s): • To examine the course of cortisol, cotison and…
Primary objective: To identify specific bacteria or a characteristic bacterial composition in the oral and gut microbiome of pSS patients compared to non-Sjögren*s syndrome sicca (non-SS sicca) patients, SLE patients and healthy controls.Secondary…
The main aim of the proposal is to study the processes involved in non-chronic vs. chronic drug seeking behavior in samples of alcohol dependent persons (ADs) and pathological gamblers (PGs) with different levels of chronicity. We thereby rely on…
To investigate the impact of 7 days of bed-rest on skeletal muscle mass, strength and whole-body insulin sensitivity in healthy, young men.
We will investigate the relationship between this permeability measure and (i) cognitive performance and (ii) the status of MRI visible cerebrovascular pathology (i.e. white matter hyperintensities, lacunar infarctions, microbleeds) in the most…
To determine if a marked change in the concentrations of one or more of the selected biomarker is evident before PUs are visible
To compare the digestion and absorption of micellar casein versus calcium-caseinate and sodium-caseinate with enzymatic cross-linking in healthy young men.
The present study will evaluate potential etiological models for sleep disturbances, depressive symptoms and cognitive impairment using an innovative idiographic design using time-series analysis that accounts for both intra-individual variability (…
In this study, the following questions will be answered:1. Does larval therapy accelerate wound healing?2. Do single larval secretions accelerate wound healing?3. Is the bacterial load in the wound reduced during larval therapy or is the microbiome…
To investigate the physical, psychological, biological and social factors that are associated with hospitalization-associated disability from hospital admission to three months post-discharge in acutely hospitalized older adults.