93 results
The purpose of this study is to determine the accuracy of the point-of-care IgE assay in atopic patients and healthy subjects. The POCT results will be compared to a reference immunoassay method for measuring this analyte.It intends to use this new…
The main objective of this study is to assess more thoroughly the differences in gait patterns between COPD patients and healthy controls. Other objectives are to assess differences in gait patterns between GOLD stages and two age groups in healthy…
Research questions: Primary questions:* Are the new point-of-care instruments for the measurement of VOCs in exhaled breath feasible for use in children and adolescents aged 6 to 20 years?* Are these techniques able to differentiate between healthy…
To assess the efficacy of an intervention directed towards prevention of clinical CF exacerbations by means of early recognition and early antibiotic treatment.
The first aim of this study is to determine the prevalence of cognitive impairment in COPD patients compared with persons without COPD and to compare cognitive functioning between patients referred by their general practitioner, patients referred by…
The first aim of this study is to determine the prevalence of cognitive impairment in COPD patients compared with persons without COPD. The second aim is to study the clinical characteristics of COPD patients with cognitive impairment. The third aim…
The purpose of this study is to test the impact of a physical activity promotion program which is a personalized, semi-automated, coaching program utilizing an smartphone on which an app is installed and coaching by the investigator. The automated…
Objective of the study is to investigate the prevalence of vitamin deficiencies of a group of Dutch elderly COPD patients. Furthermore, we will investigate if there is a relationshop between vitamin deficiencies and perceived burden of the disease.…
The main objective of this study is the clinical, physiological and psychosocial determinants of CAT in a broad sample of patients with moderate to very severe COPD and the impact of co-morbidities on the HRQL assessed with CAT. Secondary objectives…
Question: Is it an added value for the patient if there will be a default capsaicin provocation test to diagnose chronic cough?It will be investigated or with the aid of the capsaicin provocation test the diagnosis sensory hyperreactivity (SHR) can…
This study aims to determine whether the ILC populations differ in the lungs of different phenotypes of asthmatic patients and healthy subjects and how these cells are regulated by bronchial epithelial cells. Furthermore we want to study how this is…
In the present study we want to examine the effect of salbutamol on the muscle tone of the diaphragm. We also want to examine the correlation between muscle tension measured by EMG and the Clinical Asthma Score. To include the children that come to…
Primary objective:Test whether preservation of upper limb compared to lower limb muscle function is associated with preservation of functional arm use compared to functional leg use in daily life in patients with COPD compared to healthy controls.…
Validate a new activity monitor in both healthy subjects and in patients with moderate to very severe CHF or COPD.
The purpose of this study is to explore and expand the understanding of the patient's experience of physical limitations in COPD from the perspective of the patient. The information will be used to support the development of a conceptual model…
Quantify how many frail elderly aged over 65 years with reduced exercise tolerance and/or exercise induced dyspnoea have previously unrecognised COPD and heart failure.Quantify the difference in prevalence of unrecognised COPD and heart failure…
To assess the validity, reliability and responsiveness of the LRTI-VAS in non-cystic fibrosis bronchiectasis.
1. To identify breathprints of volatile organic compounds which are associated with loss of asthma control (deterioration in symptoms and lung function) after interruption of inhaled steroid therapy.2. To examine the critical VOCs of these…
- To determine the association between peanut sensitization and food related physical symptoms - To determine the association between peanut sensitization and the severity of asthma in children
The aim of this study is to investigate the course of EIB in young asthmatic children, by using a newly designed exercise provocation challenge.