14 results
First, to establish the yield of the currently propagated pancreatic cyst surveillance program, and second, to identify possible alternative surveillance strategies, which might be more (cost) effective.
The study will help us to determine 1. the necessary type of (combined) examinations and 2. the sample size that is essential to evaluate (future) genetic therapy in Usher syndrome type 2 and USH2A associated nsRP.
The primary objective of this study is to evaluate the diagnostic accuracy of physical examination and ultrasound to identify active synovial proliferation in haemophilia patients with subclinical synovial proliferation. The secondary…
Whole genome comparison between microorganisms cultured from PJI and those cultured from preoperative swabs of the patients’ microbiome, to determine the origin of the infection.
To assess inter-individual and intra-individual variation in objective skin pigmentation measurement using non-invasive colorimetry and multispectral imaging in healthy individuals and patients with skin disease.
The primary objective of this study is to isolate effects of dopamine receptor manipulation on distinct forms of working memory (WM) gating and their associated physiological changes in distinct layers of prefrontal cortex (measured with high-…
The purpose of this protocol amendment is to meet the current and future needs of the MacTel Project’s collaborating investigators and continue meeting initial objectives. In addition, a third objective is to understand the mechanisms involved in…
In this explorative study, we aim to: Analyze neoantigens expressed on different tumors of CMMRD patients, to identify more possible target antigens for DC vaccination studies and to select the antigens that are most frequent. …
Primary To evaluate the prevalence of specific immune cell subsets in a range of IMID dermatologic disease patients, both between diseases and compared to healthy volunteers Secondary To evaluate the variability in specific immune cell…
We want to remap the entire bacterial ecosystem in the gastrointestinal tract of patients with lgA nephropathy after a period of roughy two years, in order to gain insight into the processes that may play a role in the development and progression…
Primary Objective: Assess which digital health metrics are relevant to monitor for patients with (or highly suspected of having) obstructive sleep apnea before and after diagnosis, and during titration of treatment with continuous positive airway…
Generation R studies growth, development and health from early pregnancy into adulthood. The study aims to contribute to the development of strategies for optimising health and health care across the full life course.
Generation R Next aims to examine the influence of preconception and pregnancy factors on growth, development and health of children from the earliest phase of life into young adulthood. The study aims to contribute to the development of strategies…
The primary objective of this project is to evaluate the differences between a wide variety of cardiac disease and healthy volunteers using novel echocardiographic techniques (LV SV-loops, 3D RV beutels and SWI) and relate these to patient…