178 results
We presume that reducing the fasting period by adding a carbohydrate drink 2-3 hours prior to surgery is a good and feasible option to decrease orthostatic intolerance and -hypotension. Moreover, the pre- and postoperative well-being is thought to…
The hypothesis is that low dose GC therapy exerts its anti-inflammatory effect by virtue of a first-pass effect through the liver. It is difficult to directly address the hypothesis, but there is an indirect way of doing so: if indeed low dose GCs…
The aim of this study is to investigate the effect of the implementation strategy on level of implementation of palliative care and the effects on patient, informal caregiver and professional outcomes. It is hypothesized that implementation of…
To evaluate the effectiveness of eccentric calf muscle exercise therapy compared to strength training of the upper extremities (control group) in patients with chronic midportion Achilles tendinopathy.
Appropriate use and prescription of a lower limb prosthesis for people with leg amputation through or above the knee, can increase the efficiency of the integrated care around the leg prosthesis.
Discontinuation of first-line disease modifying medication (DMT) in patients with relapsing-onset multiple sclerosis that are inflammatory stable for at least 5 years, can be safely done without the return of inflammatory activity.
This study aims to apply state-of-the-art immune tests quantifying the immunosuppressive state in individuals, and the relationship between these pharmacodynamic tests and the pharmacokinetic profile (in whole blood and intracellular) after a single…
The effectiveness and cost-effectiveness of treatment with systemic cyclosporine or dupilumab in children with moderate-to-severe atopic dermatitis is different for patients with low NMF (corresponding with filaggrine-gene mutation) versus children…
Children in the game-based intervention condition will improve more on reading fluency than those in the standard intervention (TUA) condition.
(1) patient self-monitoring is not inferior to standard of care in terms of DAS 28 score; (2) patient self-monitoring in RA patients will reduce outpatient clinic visits, and will consequently decrease healthcare costs.
We expect that with a target of 1.5-2.0x baseline aPTT or with LMWH the primary composite endpoint will be reached in 60% of patients compared to 70% in usual care. To show non-inferiority with a significance level (alpha) of 5%, power of 80% and a…
Motivational coaching following exercise rehabilitation will improve physical activity behaviour (minutes of moderate- to- vigorous physical activity spent per week), measured six months after completing the exercise program.
We hypothesize that the ddPCR has a sensitivity of at least 80%
Seventy percent of patients with schizophrenia and other psychotic disorders has paranoid delusions. Paranoid delusions are associated with great distress, hospital admission and social isolation. Cognitive behavioral therapy (CBT) is the main…
The growth-mindset intervention will result in more resilient and motivated learners and better school performance than the control intervention.
The difference in surgical conditions between deep or moderate neuromuscular block is absent during sevoflurane anesthesia
The main purpose of this study is to blindly assess the effects of individual music therapy on well-being controlled for individual attention in nursing home residents with dementia who also have neuropsychiatric symptoms (NPS). The outcomes refer…
Our hypothesis is that adolescents playing the YESS! game will show a larger increase in self-management score during the first year of transition and will have a lower drop-out rate at the adult endocrine outpatient clinic (OPC), compared to…
The ingestion of a large amount of protein will results in a higher muscle protein synthetic response over a prolonged period when compared to the ingestion of a moderate amount of protein
Use of CPR as indicator for delivery in reduced fetal movements reduces perinatal mortality and improves neonatal outcome and long-term outcome.