99 results
To determine whether micellar curcumin is able to restore functional lymphocytes in pancreatic cancer patients with stable disease after standard of care treatment.
The purpose of this study is to investigate how well a new dosage form of tildrakizumab is tolerated when it is administered to healthy volunteers. Tildrakizumab (also known as Ilumetri) is no new compound; it is already available on the market as a…
The current study aims to assess the impact of self-quarantine on glycemic control. In addition, this study describes diabetes self-management, well-being and distress in Dutch patients with type 1 and type 2 diabetes, during a nationwide period of…
The primary goal of this research project is to study physiological responses of typically developing (TD) children and children with CP (only if the results of TD children are promising) to discomfort induced by the use of technological devices…
Primary Objective: This study aims to analyze cycling gross efficiency, pedalling power symmetry, and hip, knee, ankle kinematics in adults with a transtibial amputation in different foot positions and seat heightsSecondary Objective(s): The second…
The current study investigates which brain areas are related to habituation of pain (using fMRI) and enables a direct coupling with concurrent EEG. We will test the hypothesis that activation of areas in the brain show changes over time as correlate…
The primary objective of this study is to confirm that the dissolution profiles of a sugar-free and sugared lozenge containing CPC/benzocaine (1.4mg/10 mg) are comparable following a single dose in healthy adult subjects.The secondary objectives of…
Understanding the specific vs. generalized role of the prefrontal cortex for prosocial decision-making. In particular, we want to investigate whether the prefrontal cortex is recruited during the evaluation of the abstract cost-benefit ratio of one*…
The primary objective is to investigate the current prevalence of IAH and severe hypoglycaemia (SH) in individuals with diabetes type 1.The secondary objectives are:- Study the change of IAH over time in individuals with diabetes type 1.- Study risk…
Our main objective is to probe for the functional time-windows of the mid-portion of the left middle temporal gyrus (mMTG) during word comprehension and word production to determine whether the left mMTG is common to both language comprehension and…
Primary Objective:The primary objective of this study is to establish the occurrence of neutralizing antibodies to SPK-GAA capsid in participants with LOPD on an enzyme replacement regimen. Secondary Objective:The secondary objectives of this study…
The overall goal of this study is to assess the detection and discrimination of individual silently or attempted spoken words from the brain area that represents articulation of speech.To address this goal, we defined three primary objectives:1) To…
We aim to provide a neurocognitive account of communicative disabilities in patients with autism spectrum disorder (ASD), focussing on shared representations of a communicative context. We expect that ASD patients show impaired shared…
To investigate the effect of oral curcumin supplementation on different clinical parameters and the gut microbiota composition in patients with diabetes type II, inflammatory bowel disorders (both ulcerative colitis and Crohn*s disease in remission…
To quantify and assess intra- and inter-subject variability in mast cell density among healthy male and female volunteers. Serum tryptase values will also be quantified.
• Bestaan er serologische testen die geschikt zijn om doorgemaakt infecties met Sars-Cov2 aan te tonen?• Hoe wijd verspreid is Sars-Cov2 onder het zorgpersoneel en hoe verhoudt zich dat tot de Nederlandse bevolking?• Hoe ontwikkelt zich het…
To investigate differences in liking of e-liquid odors between adult smokers, young adult non-smokers, and youth non-smokers
The objective of this study is to assess the performance of the Masimo O3 regional oximeter on somatic tissue oxygenation, under controlled hypoxia. Somatic rSO2 values will be compared with combined arterial and venous blood gas measurements from…
To assess the effect of a 6-month regular, low and high dietary sweetness exposure on sweetness preferences, food intake, glucose homeostasis and body weight in healthy adults.
The primary objective of this study is to determine which candidate sensors alone or in combination are most correlated with the results from the gold standard technique breath gas analysis and blood lactic acid; and to develop an algorithm that…