47 results
In the current proposal we hypothesize that vulnerability to stress is a non-specific risk factor for developing either schizophrenia or MDD. Increased stress sensitivity is hypothesized to be related to reduced prefrontal functioning, leading to…
The objective of this observational study is the safe introduction of clinical applied IVM in The Netherlands. During this study, the number and quality of the oocytes and embryos will be studied as well as pregnancy development. Emphasis will be on…
Goal of the study is to establish evidence on cognitive biases in a high risk population and on the longitudinal impact of such biases. We hypothesize that CPAD*s show biases in their information processing when compared to control children. We…
The aim of this study is to investigate whether DWIBS may be an appropriate technique for colorectal cancer screening.
Study ObjectiveTo determine whether alprazolam, a registered anxiolytic non-selective benzodiazepine, can reduce the autonomic temperature increase induced with social stress in healthy men. Secondary objectives are to determine whether alprazolam…
To determine the reliability and feasibility of the Nanoduct sweat test system compared to the gold standard tests QPIT and Macroduct.
The main objective of this study is to evaluate outcomes and resource needs of imaging and treatment following Primovist-enhanced MRI (PV-MRI) as com¬pared to ECCM-enhanced MRI (ECCM-MRI) and contrast-enhanced CT (CE-CT) in patients with a history…
Primary Objective: To improve the detection of trauma related articular cartilage matrix damage by using a new contrast enhanced MRI technique.Secondary Objective(s): To evaluate the intraarticular changes (like proteoglycan content, disturbances in…
The primairy objective of this study is to evaluate the safety and efficacy of the Janus OPTIMA stent in the treatment of the novo lesions in native cotronary arteries with a maximum lenght of 28 mm and a diameter of 2.5 - 4.0 mm
To assess the long-term safety, tolerability and efficacy of ABT-874 in adults who have either completed or have demonstrated a loss of response (as defined in the original ABT-874 protocol) to treatment in a preceding ABT-874 study in the treatment…
This study contributes to determine if an integrated treatment for depressed elderly could be of value for depressive elderly. When this is the case, the systematically gathered data in this research, can be used and be part of the protocol of…
First, to develop a diagnostic method for non-infectious uveitis in childhood. Second, to analyze iris and ciliary body tissues of children with uveitis on the presents of inflammatory infiltrate. The results of this study will contribute in the…
This study contributes to determine if an integrated treatment for depressed elderly could be of value for depressive elderly. When this is the case, the systematically gathered data in this research, can be used and be part of the protocol of…
The primary aim of this study is to assess the effect of weight loss in obese subjects, brought about by non-surgical methods, on all types of gastroesophageal reflux (gaseous, liquid and mixed, acid and nonacid), as measured by ambulatory pH/…
Objectives: In this study we investigate possible correlations between cognitive impairment as well as response to AED treatment in children with FLE and abnormalities in brain micro-structure, function and neuronal connectivity. Therefore, we apply…
Our primary objective is to determine the incidence of EPS after kidney transplantation in patients previously treated by PD. We hypothesize that there is an increasing incidence of symptomatic and asymptomatic EPS after kidney transplantation.
Monitoring of resitance development in HIV
1) Study the chemopreventive potential of 5-ASA and UDCA in UC by evaluating the effect of treatment with these agents on ACF number, size and rate of dysplasia. 2) Gain mechanistic insight into the chemopreventive properties of 5-ASA and UDCA by…
The primary objective of the study is to demonstrate safety and efficacy of the ALIMAXX-B* covered biliary stent.The secondary objective of the study is to evaluate technical success of stent placement, , re-interventions and time to occlusion.
This pilot study aims to investigate sexual wellbeing, sexual functioning and sexual health care need within four groups of patients with major illness (COPD patients, gynaecological patients, pelvic care patients, and patients with depressive…