2618 results
Benign liver tumors and cysts carry a significant burden on the quality of life in some cases. Apart from impairing symptoms, psychological burden might provide sufficient ground for surgical intervention. There is a variable approach to them…
To evaluate the effectiveness of eccentric calf muscle exercise therapy compared to strength training of the upper extremities (control group) in patients with chronic midportion Achilles tendinopathy.
The primary objective of this study is to determine patient perspective of and satisfaction with follow-up type and frequency after THA and TKA. Therefore, we will send surveys to patients who had a THA or TKA between 1 and 15 years ago.
The primary aim of this split-mouth randomized clinical trial is to assess accuracy of bracket positioning of a fully digital IDB workflow compared to a DBB workflow, with IDB bracket planning serving as reference for both methods. The secondary…
- Six weeks of ESM combined with personalized feedback sessions, compared with treatment as usual (TAU), leads to a stronger reduction in fatigue symptoms (primary outcome clinical effectiveness). - This intervention also leads to improvements in…
Both interventions (GRAIL training & endurance and strength training (control intervention)) will result in an increase in gait speed, functional walking ability and social participation. However, the GRAIL training will result in larger…
Bone-anchored maxillary protraction therapy improves facial profile in cleft children.
Renal artery denervation (RDN) on top of pulmonary vein isolation (PVI) will improve the success of ablative therapy for patients who have paroxysmal and/or persistent atrial fibrillation, with out of range hypertension (systolic >140 mmHg or…
Subgroup 1 (complex appendicitis without mass and/or abscess formation): LA is associated with reduced superficial site infections, shorter length of stay, less costs, less pain, and better hr-QoL, compared with OA without compromising overall…
Primary Objective To describe how patients experience the first eight weeks after shoulder arthroplasty, regarding pain and pain medication, shoulder function and quality of life. To determine the direct effect of patients' expectations on…
The proportion of successful patients, defined as an improvement in LARS category, will be 25% larger in the experimental group than in the control group (in which 10 % improvement is assumed).
This multicentre randomised controlled trial aims to investigate whether PoCUS can be used as an adjunct to improve first attempt success rate in closed reductions of displaced distal radial fractures in adults in the ED.
Investigate the effect of having CYP2C19 and CYP2D6 genotypes at start of antidepressant therapy and it’s cost-effectiveness in the primary care setting.
the application of EMDR therapy is associated with a significant decrease in severity of depressive symptoms and decrease of percentage of patients meeting DSM-5 criteria for MDD compared to the waiting list. Participants receiving EMDR report after…
To optimize a safe five-day intensive intravenous insulin treatment post stroke and to assess glucose profiles in patients with stroke and HG on admission, receiving standard continues enteral tube feeding.
The main parameter of the study is evaluation and effectiveness of the treatment program on Body Mass Index (BMI) (as defined by Cole et al) compared to a standard intervention (increased physical activity and nutrient advice). Also the…
Phase IThe primary aim of the phase I part of this study is to establish the safety profile and to determine the maximum tolerated dose of Re-188-HEDP combined with Capecitabine.Phase IIThe primary aim of the phase II part of this study is to obtain…
In this study we will study the incidence of QTc-interval prolongation when combinations of 2 or more QTc-prolonging drugs are prescribed. Also we will investigate if QTc-prolongation is more frequent in patients with higher drug plasma…
The objectives of this study are:* To determine the percentage of patients with recent-onset RA and UA who achieve and maintain clinical remission on treatment with a combination of methotrexate 25 mg/week and extended prednisone pulse (tapered high…
To assess the effectiveness of misoprostol in the management of retained placenta. Will 800 micrograms of misoprostol orally reduce the need for manual removal under general anaesthesia and prove to be a safe alternative?